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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Oct 19, 2025; 15(10): 109466
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.109466
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.109466
Psychological distress and treatment adherence-challenges of patients with chronic hepatitis B: Risk factors and integrated nursing strategies
Li Dong, Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Dong L was responsible for conception, design, literature search, formal analysis, drafting and editing of the manuscript, and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li Dong, Center of Infectious Diseases, West China Hospital of Sichuan University, No. 37 Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China.
Received: June 5, 2025
Revised: July 3, 2025
Accepted: July 30, 2025
Published online: October 19, 2025
Processing time: 113 Days and 0.7 Hours
Revised: July 3, 2025
Accepted: July 30, 2025
Published online: October 19, 2025
Processing time: 113 Days and 0.7 Hours
Core Tip
Core Tip: Patients with chronic hepatitis B (CHB) often experience psychological distress, including anxiety, depression, and stigma, which significantly impairs their treatment adherence. This minireview synthesizes recent evidence on the epidemiology and psychosocial challenges faced by CHB patients and proposes a comprehensive, biopsychosocial intervention framework. The authors highlight integrated nursing strategies, including cognitive-behavioral therapy, social support systems, digital health tools, and culturally adapted care models, aimed at improving mental health outcomes and long-term adherence among CHB patients. These insights offer clinical guidance for multidisciplinary teams in hepatology and psychiatry.