Wang ZX, Gao XY, Cao YP, Li KX. Psychiatric sequelae following aneurysmal subarachnoid hemorrhage: Insights from a high-volume neurosurgical center in northern China. World J Psychiatry 2025; 15(10): 109439 [PMID: 41112615 DOI: 10.5498/wjp.v15.i10.109439]
Corresponding Author of This Article
Zhong-Xiao Wang, MD, PhD, Department of Interventional Neuroradiology, Department of Neurosurgery, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, No. 119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. zx1994824@163.com
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Clinical Neurology
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Retrospective Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Oct 19, 2025 (publication date) through Feb 28, 2026
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World Journal of Psychiatry
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2220-3206
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Wang ZX, Gao XY, Cao YP, Li KX. Psychiatric sequelae following aneurysmal subarachnoid hemorrhage: Insights from a high-volume neurosurgical center in northern China. World J Psychiatry 2025; 15(10): 109439 [PMID: 41112615 DOI: 10.5498/wjp.v15.i10.109439]
World J Psychiatry. Oct 19, 2025; 15(10): 109439 Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.109439
Psychiatric sequelae following aneurysmal subarachnoid hemorrhage: Insights from a high-volume neurosurgical center in northern China
Zhong-Xiao Wang, Xin-Yue Gao, Yun-Peng Cao, Ke-Xin Li
Zhong-Xiao Wang, Department of Interventional Neuroradiology, Department of Neurosurgery, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
Xin-Yue Gao, Yun-Peng Cao, Ke-Xin Li, Clinical College, Capital Medical University, Beijing 100070, China
Author contributions: Wang ZX performed the conceptualization, methodology, formal analysis, project administration, writing, review, and editing the manuscript, and funding acquisition; Gao XY performed the software, investigation, resources, and supervision; Cao YP performed the visualization and writing the original draft; Li KX performed the data curation and validation. All authors approved the final version manuscript.
Supported by Shenzhen Medical Academy of Research and Translation Program, No. A2302031.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Beijing Tiantan Hospital, Capital Medical University, No. KY2023-261-01.
Informed consent statement: The requirement for written informed consent was waived by the Ethics Committee of Beijing Tiantan Hospital, Capital Medical University due to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Corresponding author: Zhong-Xiao Wang, MD, PhD, Department of Interventional Neuroradiology, Department of Neurosurgery, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, No. 119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. zx1994824@163.com
Received: June 10, 2025 Revised: July 7, 2025 Accepted: July 31, 2025 Published online: October 19, 2025 Processing time: 108 Days and 0.5 Hours
Core Tip
Core Tip: In this large-scale, single-center analysis from northern China, anxiety and depression were observed in 34.9% and 31.8% of aneurysmal subarachnoid hemorrhage survivors, respectively. Female sex and the presence of multiple aneurysms were significantly associated with heightened psychological vulnerability. Additional risk factors for depression included posterior circulation aneurysm location, a family history of cerebral hemorrhage, and poor clinical outcomes. Conversely, advanced age and functional recovery emerged as protective factors. Timely identification, standardized screening, and individualized interventions may facilitate early management of post-aneurysmal subarachnoid hemorrhage emotional disturbances and ultimately enhance long-term recovery and quality of life.
