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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jun 19, 2023; 13(6): 331-339
Published online Jun 19, 2023. doi: 10.5498/wjp.v13.i6.331
Published online Jun 19, 2023. doi: 10.5498/wjp.v13.i6.331
Psychological trauma, posttraumatic stress disorder and trauma-related depression: A mini-review
Shi-Kai Wang, Min Feng, Yu Fang, Liang Lv, Gui-Lan Sun, Sheng-Liang Yang, Ping Guo, Shan-Fei Cheng, Department of Psychiatry, The Third People’s Hospital Affiliated to Huzhou University, Huzhou 313000, Zhejiang Province, China
Min-Cai Qian, Department of Neurosis and Psychosomatic Diseases, The Third People’s Hospital Affiliated to Huzhou University, Huzhou 313000, Zhejiang Province, China
Huan-Xin Chen, Department of Key Laboratory, The Third People’s Hospital Affiliated to Huzhou University, Huzhou 313000, Zhejiang Province, China
Author contributions: Wang SK contributed to the original draft; Feng M contributed to the data curation, investigation, and software; Fang Y contributed to the investigation and software; Lv L contributed to the investigation and software; Sun GL contributed to the validation and visualization; Guo P contributed to the funding acquisition and supervision; Cheng SF contributed to the visualization; Qian MC contributed to the project administration and resources; Yang SL contributed to the conceptualization and methodology; Chen HX contributed to the writing-review and editing; all authors have reviewed and approved the final version.
Supported by the Science and Technology Project of Zhejiang Provincial , No. GF22H093655 ; Nonprofit Applied Research Project of Huzhou Science and Technology Bureau , 2021GYB16.
Conflict-of-interest statement: The authors declare that there is no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ping Guo, Doctor, MD, Associate Chief Physician, Deputy Director, Department of Psychiatry, The Third People’s Hospital Affiliated to Huzhou University, No. 2088 Tiaoxi East Road, Wuxing District, Huzhou 313000, Zhejiang Province, China.
Received: December 28, 2022
Peer-review started: December 28, 2022
First decision: March 1, 2023
Revised: March 15, 2023
Accepted: May 8, 2023
Article in press: May 8, 2023
Published online: June 19, 2023
Processing time: 172 Days and 21.6 Hours
Peer-review started: December 28, 2022
First decision: March 1, 2023
Revised: March 15, 2023
Accepted: May 8, 2023
Article in press: May 8, 2023
Published online: June 19, 2023
Processing time: 172 Days and 21.6 Hours
Core Tip
Core Tip: Exposure to psychological trauma may induce posttraumatic stress disorder (PTSD) and trauma-related depression. Major depression can be a progression secondary to PTSD. Both trauma-related depression and PTSD show good response to psychotherapy or prazosin, but a poor response to conventional antidepressants, suggesting that trauma-related depression should have different pathological mechanisms, like energy metabolism deficiency. It is necessary to explore the pathogenesis of and therapeutic strategy for PTSD and trauma-related depression.