Published online Oct 19, 2023. doi: 10.5498/wjp.v13.i10.763
Peer-review started: August 8, 2023
First decision: August 24, 2023
Revised: September 1, 2023
Accepted: September 20, 2023
Article in press: September 20, 2023
Published online: October 19, 2023
Processing time: 65 Days and 2.2 Hours
Relaxation of the maternity policy has resulted in an increase in the number of elderly pregnant and lying-in women, and the prevalence of preeclampsia. Preeclampsia can lead to organ damage and system dysfunction.
To explore the factors influencing postpartum anxiety in pregnant women with preeclampsia and construct a predictive model, to provide an effective and practical risk assessment tool for clinical practice.
The object of this study is to explore the factors influencing postpartum anxiety in pregnant women with preeclampsia and construct a personalized model for predicting postpartum anxiety, to provide a reference for clinical trials.
We retrospectively analyzed 528 pregnant women with preeclampsia who delivered in our hospital between 2018 and 2021. Various physiological and biochemical indicators were obtained through laboratory tests. Multivariate logistic regression, receiver operating characteristic curve, Hosmer-Lemeshow and other methods were used to analyze the factors influencing postpartum anxiety in pregnant women with preeclampsia and to construct a predictive model.
A total of 126 pregnant women with preeclampsia experienced postpartum anxiety. Bad marital relationship, gender discrimination among family members, hematocrit, estradiol hormone and interleukin-6 were independent risk factors for postpartum anxiety in pregnant women with preeclampsia, and the predictive model constructed based on these factors had high accuracy.
We analyzed the factors influencing postpartum anxiety in pregnant women with preeclampsia and constructed a predictive model with high sensitivity and accuracy, which provided a reference value for clinical practice.
Firstly, multi-sample, multi-factor, multi-center and multi-time span clinical studies will be carried out in the future to enhance the reliability of the research results. In addition, different models were constructed for clinical application in pregnant women with preeclampsia and postpartum anxiety.