Li YJ, Zhang Y, Peng XL, Mei YJ, Yang XJ, Luo YJ. Collaborative mental health care improves well-being and reduces complications in hemodialysis patients. World J Psychiatry 2026; 16(5): 116997 [DOI: 10.5498/wjp.v16.i5.116997]
Corresponding Author of This Article
Yan-Jia Luo, Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University, No. 74 Linjiang Road, Yuzhong District, Chongqing 400010, China. sd2263922@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Randomized Controlled Trial
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
May 19, 2026 (publication date) through May 5, 2026
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Journal Information of This Article
Publication Name
World Journal of Psychiatry
ISSN
2220-3206
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Li YJ, Zhang Y, Peng XL, Mei YJ, Yang XJ, Luo YJ. Collaborative mental health care improves well-being and reduces complications in hemodialysis patients. World J Psychiatry 2026; 16(5): 116997 [DOI: 10.5498/wjp.v16.i5.116997]
Yan-Jing Li, Ying Zhang, Xi-Lan Peng, Yuan-Jun Mei, Xue-Jing Yang, Yan-Jia Luo, Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
Author contributions: Li YJ designed and performed the research and wrote the paper; Zhang Y designed the research and contributed to the analysis; Peng XL, Mei YJ and Yang XJ provided clinical advice; Luo YJ supervised the report.
Institutional review board statement: This study was approved by the Institutional Review Board of the Second Affiliated Hospital of Chongqing Medical University (Approval No. 2023-95).
Informed consent statement: Written informed consent was obtained from all participating patients and their legal guardians.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: Data of the research available from the corresponding author. Participants gave informed consent for data sharing.
Corresponding author: Yan-Jia Luo, Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University, No. 74 Linjiang Road, Yuzhong District, Chongqing 400010, China. sd2263922@163.com
Received: November 25, 2025 Revised: December 29, 2025 Accepted: February 10, 2026 Published online: May 19, 2026 Processing time: 155 Days and 0.2 Hours
Abstract
BACKGROUND
Chronic kidney disease (CKD) and the maintenance hemodialysis (MHD) it necessitates impose significant physical and psychological burdens on patients, including high rates of anxiety, depression, and various physiological complications, which severely impair their quality of life.
AIM
To investigate the effects of a collaborative care model combined with mental health education on the psychological status and complications in patients with CKD undergoing MHD.
METHODS
A total of 128 patients who underwent hemodialysis at the Hemodialysis Center of the Second Affiliated Hospital of Chongqing Medical University between April 2023 and March 2025 were enrolled and randomly assigned to a control group (n = 64) or study group (n = 64). The control group received routine hemodialysis management plus mental health education, whereas the study group also received a collaborative care model intervention. After eight weeks of intervention, psychological status [Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS)], quality of life [World Health Organization Quality of Life-BREF (WHOQOL-BREF) and Kidney Disease Quality of Life (KDQOL)], symptom improvement, and complication rates were compared between the groups.
RESULTS
The SAS and SDS scores in the intervention group were significantly lower than those in the control group (both P < 0.05). Post-intervention WHOQOL-BREF scores in the physical health, psychological health, social relationships, and environmental domains increased in both groups, with significantly higher scores in the intervention group (P < 0.05). Similarly, both the general health status and kidney disease-specific domain scores of the KDQOL improved in both groups, with greater improvements in the study group (P < 0.05). The incidences of hypertension (P = 0.047), hypotension (P = 0.042), and anemia (P = 0.028) were significantly lower in the study group than in the control group, whereas no significant difference was observed in the infection rates (P > 0.05).
CONCLUSION
The collaborative care model combined with mental health education had significant positive effects on the psychological well-being and complication control in patients with CKD undergoing MHD. This approach may be widely used in clinical practice to improve nursing care for patients undergoing MHD.
Core Tip: This study demonstrates that a collaborative care model combined with structured mental health education significantly improves psychological well-being, quality of life, and complication management in patients with chronic kidney disease undergoing maintenance hemodialysis. The findings highlight the importance of integrating family involvement and multidisciplinary support into hemodialysis care to enhance both physical and mental health outcomes.
