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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. May 19, 2026; 16(5): 115088
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.115088
Medical mistrust and its association with cyberchondria: A cross-sectional study among Lebanese adults
Nariman Salem, Joudi El Wazze, Rawan Jalloul, Hussein Kaddoura, Siham Kaddoura, Ali Mansour, Ali Msheik, Atef Salame Nasreddine, Ali Zaiour, Issa Zalzali, Lynn Nasr
Nariman Salem, Department of Anesthesiology, Beirut Arab University, Beirut 0000, Beyrouth, Lebanon
Joudi El Wazze, Rawan Jalloul, Hussein Kaddoura, Siham Kaddoura, Ali Mansour, Ali Msheik, Atef Salame Nasreddine, Ali Zaiour, Issa Zalzali, Department of Internal Medicine, Beirut Arab University, Beirut 0000, Beyrouth, Lebanon
Lynn Nasr, Department of Psychiatry, Saint George University of Beirut, Beirut 1100, Beyrouth, Lebanon
Author contributions: Salem N contributed to the project administration; El Wazze J contributed to the visualization; Salame Nasreddine A contributed to the critical revision of the manuscript; Mansour A contributed to the formal analyses; Zaiour A contributed to the resources; El Wazze J and Mansour A contributed to the data interpretation; Jalloul R and Kaddoura S contributed to writing the original draft; Jalloul R, Kaddoura S, and Msheik A contributed to the data curation; El Wazze J, Jalloul R, and Kaddoura H contributed to the literature review; Salem N, Kaddoura S, Salame Nasreddine A, and Nasr L contributed to the conceptualization; Salem N, Mansour A, and Nasr L contributed to the methodology; Kaddoura S, Kaddoura H, Mansour A, Msheik A, and Zalzali I contributed to the data collection; Salem N, Salame Nasreddine A, and Nasr L contributed to the supervision; Salem N, El Wazze J, Jalloul R, Kaddoura H, Kaddoura S, Mansour A, Msheik A, Zaiour A, Zalzali I, and Nasr L contributed to the writing, review, and editing of the manuscript; All authors contributed to the interpretation of the findings, revised the manuscript critically for important intellectual content, and approved the final version.
Institutional review board statement: The study was approved by the institutional review board of Beirut Arab University (Approval No. FWA00019120).
Informed consent statement: Electronic informed consent was obtained from all participants prior to their enrolment in the study. Participation was voluntary, and all responses were collected anonymously.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets generated and analyzed during the current study are not publicly available due to privacy and confidentiality restrictions but are available from the corresponding author on reasonable request.
Corresponding author: Lynn Nasr, MD, Department of Psychiatry, Saint George University of Beirut, Ashrafieh, Beirut 1100, Beyrouth, Lebanon. lynnasr@proton.me
Received: October 13, 2025
Revised: November 22, 2025
Accepted: February 5, 2026
Published online: May 19, 2026
Processing time: 204 Days and 2.1 Hours
Abstract
BACKGROUND

Medical mistrust, defined as a lack of confidence in physicians and healthcare institutions, has been linked to poorer adherence, vaccine hesitancy, and reduced engagement with care. In parallel, cyberchondria, characterized by excessive and anxiety-driven online health information seeking, has emerged as a growing concern, particularly in settings where trust in healthcare systems is strained. In Lebanon, recurrent economic, political, and health system crises may amplify both mistrust and reliance on online sources; however, the relationship between medical mistrust and cyberchondria has not been examined.

AIM

To evaluate the relationship between medical mistrust and cyberchondria among Lebanese adults and to examine their association with previous medical errors.

METHODS

A cross-sectional online survey was conducted between August and October 2022 among 474 Lebanese residents aged ≥ 18 years, recruited using convenience and snowball sampling via social media and community networks. The questionnaire collected sociodemographic data, physical and mental health history, coronavirus disease 2019 (COVID-19) vaccination status and trust, and previous experiences of misdiagnosis or mistreatment. Medical mistrust was measured with the 17-item Medical Mistrust Index (MMI-17), and cyberchondria with the 12-item Short Cyberchondria Severity Scale (CSS-12). Data were analyzed using descriptive statistics, independent-samples t-test, analysis of variance, and simple linear regression, with a significance level of P < 0.05.

RESULTS

The sample was predominantly young adults, with a slight female majority and over half being students. Higher MMI-17 scores were observed among males, participants aged 26 years to 35 years, those reporting mental health conditions, individuals who lacked trust in the COVID-19 vaccine, and those with a history of misdiagnosis, mistreatment, loss of a relative due to medical error, or preference for herbal medicine. Higher CSS-12 scores were found among males, residents of certain governorates, participants with physical or mental health conditions, those who did not trust the COVID-19 vaccine, and individuals reporting previous misdiagnosis, loss due to medical error, or preference for herbal medicine. In simple linear regression, medical mistrust was positively associated with cyberchondria (unstandardized β approximately 0.37; P < 0.001), with medical mistrust explaining a small proportion of the variance in CSS-12 scores (R2 approximately 0.03).

CONCLUSION

The sample was predominantly young adult students, with a slight female majority. Higher MMI-17 scores were observed among males; participants aged 26 to 35 years; those reporting mental health conditions; individuals who lacked trust in the COVID-19 vaccine; and those with a history of misdiagnosis, mistreatment, loss of a relative due to medical error, or preference for herbal medicine. Higher CSS-12 scores were found among males; residents of certain governorates; participants with physical or mental health conditions; those who did not trust the COVID-19 vaccine; and individuals reporting previous misdiagnosis, loss due to medical error, or preference for herbal medicine. In simple linear regression, medical mistrust was positively associated with cyberchondria (unstandardized β approximately 0.37; P < 0.001), with medical mistrust explaining a small proportion of the variance in CSS-12 scores (R2 approximately 0.03).

Keywords: Medical mistrust; Cyberchondria; Health anxiety; Medical errors; Patient-physician communication

Core Tip: This study explored the relationship between medical mistrust and cyberchondria among Lebanese adults. A significant positive correlation was identified, indicating that individuals with higher medical mistrust scores were more likely to exhibit severe cyberchondria behaviors. Previous medical errors, mental health conditions, and vaccine hesitancy were key contributing factors. Addressing patient physician communication and restoring trust in healthcare systems may help mitigate excessive online health-information seeking and improve health outcomes.

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