Published online Feb 19, 2026. doi: 10.5498/wjp.v16.i2.111577
Revised: August 1, 2025
Accepted: November 7, 2025
Published online: February 19, 2026
Processing time: 211 Days and 1.4 Hours
Psychological treatments such as exposure and response prevention (ERP) or cognitive behavioral therapy are effective in obsessive-compulsive disorder (OCD), either on their own or in combination with medications. However, very few patients receive ERP or cognitive behavioral therapy. Digital-delivered psy
To examine the VC-delivered ERP’s feasibility, acceptability, efficacy, and long-term outcomes and compare its efficacy with inpatient ERP.
This study compared VC ERP’s pre- and post-intervention efficacy (n = 20) with a matched group of patients who had undergone inpatient ERP (n = 17). The Yale-Brown Obsessive-Compulsive Scale (YBOCS) scores rated the efficacy of ERP. The feasibility outcomes for VC-delivered ERP included the operational capacity, treatment utilization, treatment engagement, use of other services, and adverse events. Treatment satisfaction and preferences among users determined acceptability. Long-term follow-up determined whether patients were in remission based on the YBOCS scores and other criteria.
The sample had 97 patients with OCD. The patients had severe (YBOCS score 27) and chronic (6 years) OCD with psychiatric comorbidity (51%). The refusal rate for VC-ERP was 11%, and the dropout rate was 19%. VC-ERP failed in 29% with treatment-resistant OCD. The 20 patients who completed VC-ERP had 85% redu
Despite its methodological limitations, this study suggests that VC-delivered ERP is feasible, acceptable, and as efficacious as in-person ERP for OCD in the resource-constrained settings of low- and middle-income countries.
Core Tip: Videoconferencing (VC) delivered exposure and response prevention (ERP) may be suitable for the treatment of obsessive-compulsive disorder (OCD) in low-resource settings, but there are no trials. This study examined the feasibility, acceptability, efficacy, and long-term outcomes of VC-delivered ERP in 97 patients with OCD and compared its efficacy with inpatient ERP. Despite its methodological limitations, this study suggests that VC-delivered ERP was feasible, acceptable, and as efficacious as in-person ERP. Gains from VC-ERP persisted for more than 2 years. VC-delivered ERP is a viable treatment option for OCD in the resource-constrained settings of low- and middle-income countries.
