Li N, Zhao J, Tang YP, Niu YQ. Motivational psychological nursing reduces anxiety and depression in patients with rheumatic and immunological diseases combined with nephropathy. World J Psychiatry 2025; 15(12): 108449 [PMID: 41357929 DOI: 10.5498/wjp.v15.i12.108449]
Corresponding Author of This Article
Jing Zhao, Department of Nephrology, Shaanxi Provincial People's Hospital, No. 256 Youyi West Road, Xi’an 710068, Shaanxi Province, China. m18049468272@163.com
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Psychology
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Retrospective Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dec 19, 2025 (publication date) through Dec 9, 2025
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World Journal of Psychiatry
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2220-3206
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Li N, Zhao J, Tang YP, Niu YQ. Motivational psychological nursing reduces anxiety and depression in patients with rheumatic and immunological diseases combined with nephropathy. World J Psychiatry 2025; 15(12): 108449 [PMID: 41357929 DOI: 10.5498/wjp.v15.i12.108449]
World J Psychiatry. Dec 19, 2025; 15(12): 108449 Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.108449
Motivational psychological nursing reduces anxiety and depression in patients with rheumatic and immunological diseases combined with nephropathy
Ning Li, Jing Zhao, Yu-Ping Tang, Ya-Qi Niu
Ning Li, Ya-Qi Niu, Department of Rheumatology and Immunology, Shaanxi Provincial People's Hospital, Xi’an 710068, Shaanxi Province, China
Jing Zhao, Department of Nephrology, Shaanxi Provincial People's Hospital, Xi’an 710068, Shaanxi Province, China
Yu-Ping Tang, Department of Rheumatology and Immunology, The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
Author contributions: Li N initiated the research, Tang YP and Li N designed experiments and conducted clinical data collection, followed up after surgery and collected data; Zhao J and Niu YQ organized and statistically analyzed the data; Li N and Zhao J made key revisions to important knowledge content; all authors have read and approved the final version.
Institutional review board statement: This study was approved by the Ethics Committee of Shaanxi Provincial People's Hospital.
Informed consent statement: The Ethics Committee agreed to waive informed consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jing Zhao, Department of Nephrology, Shaanxi Provincial People's Hospital, No. 256 Youyi West Road, Xi’an 710068, Shaanxi Province, China. m18049468272@163.com
Received: June 13, 2025 Revised: July 18, 2025 Accepted: October 11, 2025 Published online: December 19, 2025 Processing time: 167 Days and 1.5 Hours
Abstract
BACKGROUND
The coexistence of rheumatological and immunological diseases with nephropathy presents considerable clinical challenges. These challenges often result in heightened anxiety and depression, which detrimentally affect patient outcomes. Motivational psychological nursing, which incorporates motivational interview and cognitive-behavioral therapy, may offer a promising approach to address these psychological concerns.
AIM
To evaluate the effectiveness of motivational psychological nursing in the reduction of anxiety and depression and improvement of the quality of life of patients with rheumatological and immunological diseases complicated by nephropathy.
METHODS
We conducted a retrospective cohort study involving 206 patients with rheumatological and immunological diseases complicated by nephropathy and who were treated between January 2021 and January 2025. The inclusion criteria were as follows: Aged 18-75 years, met the diagnostic criteria for rheumatological and immunological diseases with a renal biopsy classification above type II, hospitalized in our facility, received consistent basic nursing care, and had complete clinical data available. Participants allotted to the observation group (n = 102) receiving motivational psychological nursing, and those in the control group (n = 104) received standard care. Psychological status was assessed using Self-Rating Anxiety Scale (SAS), Beck Anxiety Inventory, Hamilton Anxiety Rating Scale, Self-Rating Depression Scale (SDS), Patient Health Questionnaire-9, and other standardized measures. Intervention lasted throughout hospitalization, with follow-up assessments conducted before discharge.
RESULTS
Pre-intervention, anxiety, and depression scores were similar across groups. Postintervention, the observation group showed significant reductions in anxiety (SAS: 44.53 ± 6.72 vs 46.79 ± 6.94; P = 0.018) and depression (SDS: 45.20 ± 5.07 vs 46.97 ± 5.25; P = 0.014) compared with the control group. General self-efficacy (P = 0.044), health-related quality of life (P = 0.044), and World Health Organization Quality of Life (P = 0.040) scores also revealed significant improvement.
CONCLUSION
Motivational psychological nursing considerably reduces anxiety and depression in patients with rheumatological and immunological diseases complicated by nephropathy, which enhances the overall quality of life.
Core Tip: This study investigates the impact of motivational psychological nursing on anxiety and depression in patients with rheumatological and immunological diseases complicated by nephropathy. By integrating motivational interviewing and cognitive-behavioral therapy, our findings demonstrate significant reductions in anxiety and depression scores, alongside improvements in self-efficacy and quality of life, highlighting a promising therapeutic approach for this complex patient group.
