Cox health behavior intervention combined with psychological care for patients with hypertensive cerebral hemorrhage and mental disorders

doi:10.5498/wjp.v15.i10.106904

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Oct 19, 2025 (publication date) through Feb 27, 2026

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

World J Psychiatry. Oct 19, 2025; 15(10): 106904
Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.106904

Cox health behavior intervention combined with psychological care for patients with hypertensive cerebral hemorrhage and mental disorders

Ning-Di Lu, Jing-Jing Zhou, Fei Huang

Ning-Di Lu, Jing-Jing Zhou, Fei Huang, Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China

Author contributions: Lu ND designed the study and was involved in the data collection and manuscript preparation; Lu ND, Zhou JJ, and Huang F reviewed the manuscript; and all authors read and approved the final manuscript.

Institutional review board statement: This study was approved by the Medical Ethics Committee of the Affiliated Hospital of Nantong University, approval No. NT-DXFSYR-12/20220101.

Clinical trial registration statement: The study was registered at the Clinical Trial Center (www.researchregistry.com) with registration number: Researchregistry11302.

Informed consent statement: All study participants and their legal guardians provided written informed consent before enrollment.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.

Data sharing statement: No additional data are available.

Corresponding author: Ning-Di Lu, Nurse in Charge, Department of Neurosurgery, Affiliated Hospital of Nantong University, No. 688 Qingnian East Road, Tongzhou District, Nantong 226001, Jiangsu Province, China. lnd13773618351@yeah.net

Received: May 20, 2025
Revised: June 18, 2025
Accepted: August 4, 2025
Published online: October 19, 2025
Processing time: 128 Days and 23.4 Hours

Abstract

BACKGROUND

Cox health behavior interventions combined with psychological care have the potential to improve recovery outcomes and psychological well-being in patients with hypertensive cerebral hemorrhage accompanied by mental disorders.

AIM

To explore the impact of combining the Cox Health Behavior Interaction Model with multifaceted psychological nursing in patients with hypertensive intracerebral hemorrhage (ICH) complicated by mental disorders and to provide a reference for the nursing intervention in patients with hypertensive ICH.

METHODS

Overall, 128 patients with hypertensive ICH complicated by mental disorders who were admitted to the Affiliated Hospital of Nantong University between January 2022 and December 2024 were divided into groups using a random number table. The control group (n = 64) received multifaceted psychological nursing, and the observation group (n = 64) received the Cox Health Behavior Interaction Model intervention based on multifaceted psychological nursing. The mental state, psychological resilience, self-efficacy, and quality of life of the two groups were compared.

RESULTS

Post-intervention, the mental states of anxiety and depression in the observation group (38.82 ± 3.67 points and 35.14 ± 2.75 points, respectively) were lower than those in the control group (46.96 ± 5.12 points and 41.36 ± 3.71 points, respectively), and the psychological resilience levels (tenacity, self-improvement, and optimism) were higher than those in the control group (P < 0.05). Post-intervention, the General Self-Efficacy Scale score in the observation group (31.75 ± 2.75 points) was higher than that in the control group (26.76 ± 2.93 points), and the physical health- and social and mental health-related quality of life were both higher than those in the control group (P < 0.05).

CONCLUSION

Combining the Cox Health Behavior Interaction Model with multifaceted psychological nursing for patients with hypertensive ICH and mental disorders relieves anxiety and depression and improves resilience, self-efficacy, and quality of life.

Keywords: Cox Health Behavior Interaction Model; Multifaceted psychological nursing; Hypertensive intracerebral hemorrhage; Mental disorders; Clinic

Core Tip: Reasonable and timely intervention is crucial for patients suffering from hypertensive intracerebral hemorrhage, as it can significantly improve prognosis and reduce the risk of complications. This is especially important for individuals who also suffer from coexisting mental disorders, as their condition may complicate clinical management, delay recovery, and impact treatment adherence. A comprehensive, multidisciplinary approach is therefore essential to address both neurological and psychiatric aspects effectively.