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Letter to the Editor
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
World J Clin Pediatr. Mar 9, 2026; 15(1): 114152
Published online Mar 9, 2026. doi: 10.5409/wjcp.v15.i1.114152
Mucopolysaccharidosis type VI in the Russian registry: Further insights and considerations
Sajid Malik
Sajid Malik, Department of Zoology, Faculty of Biological Sciences, Quaid-I-Azam University, Islamabad 45320, Pakistan
Author contributions: Malik S conceived the idea, wrote the manuscript, and approved the final manuscript.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Corresponding author: Sajid Malik, PhD, Department of Zoology, Faculty of Biological Sciences, Quaid-I-Azam University, University Road, Islamabad 45320, Pakistan. malik@qau.edu.pk
Received: September 15, 2025
Revised: October 17, 2025
Accepted: December 16, 2025
Published online: March 9, 2026
Processing time: 175 Days and 3.2 Hours
Core Tip

Core Tip: This commentary highlights major methodological and reporting limitations in the recent mucopolysaccharidosis type VI Russian national registry study by Vechkasova et al, including missing statistical analyses, unclear genotype-phenotype correlations, inconsistent data reporting, and survivorship bias. Improving data transparency, variant interpretation, and clinical documentation is essential for the registry to generate reliable insights and guide patient care.