Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Dec 9, 2025; 14(4): 109877
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.109877
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.109877
Rare case of respiratory syncytial virus induced myocarditis in a neonate: A case report
Lema S K Jaber, Mo'ath Abu-hamdeh, Duha G M Yadak, Department of Pediatrics, Annajah National University, Nablus P400, West Bank, Palestine
Mahmoud Qouqas, Jamal Abdullah, Rasmea M Asad, Anas Manhal, Department of Pediatrics, Hebron University, Hebron P720, West Bank, Palestine
Co-first authors: Lema S K Jaber and Mo'ath Abu-hamdeh.
Author contributions: Jaber LSK and Abu-Hamdeh M contributed equally to this work and are co–first authors. Jaber LSK is the corresponding author; Jaber LSK and Abu-Hamdeh M conceptualized the case and contributed to patient care, data collection, and manuscript drafting; Qouqas M conducted the literature review, coordinated diagnostic workup, and assisted with manuscript editing; Abdullah J managed clinical care and contributed to supportive treatment planning and manuscript review; Asad RM analyzed laboratory data, assisted in diagnostic interpretation, and proofread the manuscript; Manhal A interpreted imaging studies, contributed to clinical data interpretation, and reviewed the manuscript; Yadak DGM conducted the final literature review and supported manuscript formatting and submission; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest regarding the publication of this case report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lema S K Jaber, MD, Department of Pediatrics, Annajah National University, Amriyah, Nablus P400, West Bank, Palestine. limajabr7@gmail.com
Received: May 30, 2025
Revised: June 30, 2025
Accepted: August 20, 2025
Published online: December 9, 2025
Processing time: 154 Days and 5.6 Hours
Revised: June 30, 2025
Accepted: August 20, 2025
Published online: December 9, 2025
Processing time: 154 Days and 5.6 Hours
Core Tip
Core Tip: We report a rare case of respiratory syncytial virus (RSV)-induced myocarditis in a 26-day-old neonate initially diagnosed with bronchiolitis. Early cardiac evaluation revealed elevated t troponin levels, a reduced ejection fraction, and mitral regurgitation. Multimodal management, including corticosteroids, L-carnitine, vitamin D, and conventional cardiac therapies, led to full recovery. This case highlights the diagnostic challenges of RSV myocarditis in neonates and emphasizes the potential value of adjunctive therapies targeting immune modulation and mitochondrial support. Early recognition and a personalized approach may improve outcomes in this under-diagnosed complication of RSV infection.