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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Dec 9, 2025; 14(4): 108133
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.108133
Published online Dec 9, 2025. doi: 10.5409/wjcp.v14.i4.108133
Increasing prevalence of congenital hypothyroidism emerges as a growing concern in Jordan
Manar Al-Lawama, Rasha Odeh, Abeer AlAssaf, Jumana Albaramki, Esraa Arabiat, Salam Al-Kayed, Department of Pediatrics, The University of Jordan, Amman 11940, Amman, Jordan
Nour Ghanem, Department of Pediatrics, Al-Balqa` Applied University, Salt 19117, Salt, Jordan
Dina Abu Assab, Hadeel Alzoubi, Department of Pediatrics, Istishari Hospital, Amman 11942, Amman, Jordan
Aseel Al-Dmour, Department of Pediatrics, Mutah University, Al Karak 61710, Jordan
Arwa Kiswani, Department of Pediatrics, King Hussain Cancer Center, Amman 11941, Amman, Jordan
Saleh Al Jbour, Department of Surgery, Royal Medical services, Amman 11855, Amman, Jordan
Author contributions: Al-Lawama M contributed to conceptualization, study design, data analysis, and manuscript writing; Odeh R and AlAssaf A contributed to clinical input, analysis, and manuscript review; Odeh R, AlAssaf A and Albaramki J contributed to final approval; Albaramki J, Ghanem N, Abu Assab D, Al-Dmour A, Arabiat E, Kiswani A, Al-Kayed S, Alzoubi H and Al Jbour S contributed to literature review; Ghanem N, Abu Assab D, Al-Dmour A, Arabiat E, Kiswani A, Al-Kayed S and Alzoubi H contributed to preliminary analysis and manuscript draft writing; Al Jbour S contributed to approval of the final manuscript.
Institutional review board statement: Ethical approval was obtained from the Deanship of Scientific Research at the University of Jordan and the Institutional Review Board Committee at the University of Jordan Hospital.
Informed consent statement: The study is a retrospective anonymized file review. The consent is waived.
Conflict-of-interest statement: All authors declare no conflict of interest.
Data sharing statement: The data is available upon reasonable request at m.allawama@ju.edu.jo.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Manar Al-Lawama, MD, Professor, Department of Pediatrics, The University of Jordan, Queen Rania Street, Amman 11940, Amman, Jordan.
Received: April 7, 2025
Revised: May 21, 2025
Accepted: June 17, 2025
Published online: December 9, 2025
Processing time: 209 Days and 3.7 Hours
Revised: May 21, 2025
Accepted: June 17, 2025
Published online: December 9, 2025
Processing time: 209 Days and 3.7 Hours
Core Tip
Core Tip: This study reveals a high incidence of congenital hypothyroidism (1 in 400 live births) in Jordan, a significant increase from previously reported rates. It emphasizes the importance of TSH screening with a cutoff of < 5 mU/L and advocates for further investigation into the underlying causes and risk factors for CH in the Jordanian population.