Biological approaches and biomaterial-based solutions for bone reconstruction: A comprehensive review

doi:10.5312/wjo.v17.i4.116707

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Orthop. Apr 18, 2026; 17(4): 116707
Published online Apr 18, 2026. doi: 10.5312/wjo.v17.i4.116707

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Figure 1 Illustrative representation of the stages of bone remodeling, highlighting the sequential processes of resorption, reversal, and formation.

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Figure 2 Comparative schematic representation between platelet-rich fibrin and platelet-rich plasma, emphasizing their structural and compositional differences. PRF: Platelet-rich fibrin; PRP: Platelet-rich plasma.

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Figure 3 Illustrative representation of the cellular effects of photobiomodulation therapy using low-level laser therapy. LLLT: Low-level laser therapy; ATP: Adenosine triphosphate.

Citation: Horvath Pereira BO, Horvath-Pereira BO, Reis CHB, da Silva ELR, da Silva-Júnior LN, Buchaim RL, Buchaim DV. Biological approaches and biomaterial-based solutions for bone reconstruction: A comprehensive review. World J Orthop 2026; 17(4): 116707
URL: https://www.wjgnet.com/2218-5836/full/v17/i4/116707.htm
DOI: https://dx.doi.org/10.5312/wjo.v17.i4.116707