Potential prognostic biomarkers in pancreatic juice of resectable pancreatic ductal adenocarcinoma

doi:10.5306/wjco.v8.i3.255

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 8, Issue 3

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (13122)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-4) series, Tables (1-1) series.

Item

Count

PDF

793

WORD

444

HTML

4476

Figures (1-4)

361

Tables (1-1)

970

Sum=7044

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

981

Download

1727

Sum=2708

Publishing Process of This Article

Item

Count

Browse

1412

Download

1961

Sum=3373

Jun 10, 2017 (publication date) through Feb 28, 2026

Times Cited of This Article

Times Cited (12)

Journal Information of This Article

Publication Name

World Journal of Clinical Oncology

ISSN

2218-4333

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Minireviews

World J Clin Oncol. Jun 10, 2017; 8(3): 255-260
Published online Jun 10, 2017. doi: 10.5306/wjco.v8.i3.255

Potential prognostic biomarkers in pancreatic juice of resectable pancreatic ductal adenocarcinoma

Shefali Agrawal

Shefali Agrawal, Hepatobiliary and Pancreatic Surgery, Department of Surgical Oncology, Indraprastha Apollo Hospitals, New Delhi 110076, India

Author contributions: Agrawal S solely contributed to this paper.

Conflict-of-interest statement: None.

Correspondence to: Shefali Agrawal, MD, MS, FACS, Senior Consultant, Hepatobiliary and Pancreatic Surgery, Department of Surgical Oncology, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi 110076, India. shefali_a@apollohospitals.com

Telephone: +91-81-30009660

Received: December 15, 2016
Peer-review started: December 19, 2016
First decision: March 27, 2017
Revised: April 1, 2017
Accepted: May 12, 2017
Article in press: May 13, 2017
Published online: June 10, 2017
Processing time: 168 Days and 8.5 Hours

Core Tip

Core tip: Pancreatic juice is a rich source of cancer-specific proteins rendering it a promising tool for identifying novel biomarkers in pancreatic ductal adenocarcinoma. Recent proteomic and microRNA expression analyses have identified several diagnostic and prognostic biomarkers. Elevated carcinoembryonic antigen (CEA) in bile is a marker of malignancy and a predictor of hepatic recurrence. The potential of cancer antigen 19-9, CEA and lactate dehydrogenase as prognostic biomarkers in pancreatic juice and bile is unknown. Specimens of pancreatic juice and bile can be readily collected during pancreatic resection. Profiling of pancreatic juice and bile to identify novel biomarkers may facilitate early diagnosis and improve selection of patients for adjuvant therapy.