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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Nov 24, 2025; 16(11): 111764
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.111764
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.111764
Dynamic esophageal manometry reveals pseudoachalasia secondary to metastatic breast cancer: A case report
Hong-Yan Pan, Wei Ding, Zhi-Mo Wang, Yan-Yan Feng, Chun-Sheng Cheng, Division of Gastroenterology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, Guangdong Province, China
Wei Liu, Department of Pathology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, Guangdong Province, China
Ai-Hua Yu, Department of Orthopaedics, Zhijiang People’s Hospital, Zhijiang 443200, Hubei Province, China
Author contributions: Pan HY contributed to conceptualization; Feng YY contributed to formal analysis; Pan HY and Wang ZM contributed to investigation; Yu AH and Liu W contributed to data curation; Pan HY and Ding W contributed to writing-original draft preparation; Pan HY and Feng YY contributed to writing-review and editing; Cheng CS contributed to supervision; all authors have read and agreed to the published version of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Sheng Cheng, Chief Physician, Division of Gastroenterology, Huazhong University of Science and Technology Union Shenzhen Hospital, No. 89 Taoyuan Road, Nanshan District, Shenzhen 518052, Guangdong Province, China.
Received: July 8, 2025
Revised: August 28, 2025
Accepted: November 4, 2025
Published online: November 24, 2025
Processing time: 135 Days and 20.6 Hours
Revised: August 28, 2025
Accepted: November 4, 2025
Published online: November 24, 2025
Processing time: 135 Days and 20.6 Hours
Core Tip
Core Tip: This case report presents a rare instance of pseudoachalasia secondary to metastatic breast cancer following surgery. Notably, high-resolution manometry (HRM) detected rapid changes in esophageal motility, progressing from normal motility to type II achalasia within a brief interval. This dynamic progression highlighted the diagnostic value of HRM in distinguishing pseudoachalasia from primary achalasia. The report emphasizes the importance of considering malignancy-related secondary achalasia in patients with a cancer history and unexplained dysphagia. It advocates for early HRM evaluation and pathological confirmation to guide timely treatment.