©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Jan 24, 2025; 16(1): 97163
Published online Jan 24, 2025. doi: 10.5306/wjco.v16.i1.97163
Published online Jan 24, 2025. doi: 10.5306/wjco.v16.i1.97163
Sine oculis homeobox homolog family function in gastrointestinal cancer: Progression and comprehensive analysis
Yang-Zheng Lan, Zheng Wu, Wen-Jia Chen, Jing Liu, Department of The Breast Center, Cancer Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
Xin-Ning Yu, Hua-Tao Wu, Department of General Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
Author contributions: Liu J and Lan YZ designed this study; Lan YZ, Wu Z, Chen WJ, and Yu XN searched the publications; Lan YZ, Wu Z, Chen WJ, Yu XN, Wu HT, and Liu J interpreted the results, constructed the structure of the review, and prepared the tables; Lan YZ prepared the draft of the manuscript; Lan YZ and Wu Z prepared the figures; Liu J revised the manuscript critically; All authors read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82273457; the Natural Science Foundation of Guangdong Province, No. 2023A1515012762 and No. 2021A1515010846; Special Grant for Key Area Programs of Guangdong Department of Education, No. 2021ZDZX2040; and Science and Technology Special Project of Guangdong Province, No. 210715216902829.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Corresponding author: Jing Liu, MD, PhD, Senior Scientist, Department of The Breast Center, Cancer Hospital of Shantou University Medical College, No. 22 Xinling Road, Shantou 515041, Guangdong Province, China. jliu12@stu.edu.cn
Received: May 25, 2024
Revised: September 20, 2024
Accepted: October 20, 2024
Published online: January 24, 2025
Processing time: 158 Days and 7.2 Hours
Revised: September 20, 2024
Accepted: October 20, 2024
Published online: January 24, 2025
Processing time: 158 Days and 7.2 Hours
Core Tip
Core Tip: The sine oculis homeobox homolog gene family, crucial for embryonic development and implicated in tumors, shows promise for targeted therapies in gastrointestinal tumors. Understanding its diverse roles can lead to advances in diagnosis, prognosis, and treatment of gastrointestinal cancers.