Clinical and Translational Research
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Feb 24, 2024; 15(2): 243-270
Published online Feb 24, 2024. doi: 10.5306/wjco.v15.i2.243
Identification of immune cell-related prognostic genes characterized by a distinct microenvironment in hepatocellular carcinoma
Meng-Ting Li, Kai-Feng Zheng, Yi-Er Qiu
Meng-Ting Li, Kai-Feng Zheng, Yi-Er Qiu, Department of Gastroenterology, The Affiliated People's Hospital of Ningbo University, Ningbo 315000, Zhejiang Province, China
Author contributions: Li MT contributed to writing-original draft; Zheng KF contributed to writing-reviewing and editing; Qiu YE contributed to supervision.
Institutional review board statement: Our research was conducted based on public datasets, and no human subjects were involved in this research. Thus, there is no need to obtain approval by the institutional review board.
Informed consent statement: Our research was conducted based on public datasets, and no human subjects were involved in this research. Thus, there is no need to obtain informed consent.
Conflict-of-interest statement: All the authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Data sharing statement: The data sets supporting the results of this article are all included in the article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Meng-Ting Li, MD, PhD, Doctor, Department of Gastroenterology, The Affiliated People's Hospital of Ningbo University, No. 251 Baizhang East Road, Ningbo 315000, Zhejiang Province, China. limengting1992@foxmail.com
Received: October 18, 2023
Peer-review started: October 18, 2023
First decision: November 17, 2023
Revised: December 4, 2023
Accepted: January 11, 2024
Article in press: January 11, 2024
Published online: February 24, 2024
Processing time: 125 Days and 2.8 Hours
Core Tip

Core Tip: In this work, we focused on establishing a prognostic survival model with seven prognostic genes to predict overall survival in patients with hepatocellular carcinoma (HCC) and revealing the tumor microenvironment based on intersecting genes of The Cancer Genome Atlas and The Cancer Genome Atlas datasets. In addition, potential chemotherapy drugs could provide useful insights into the potential clinical treatment of HCC.