Ma Y, Jia B, He XJ, Cai YX, Chen JY, Zhong JX. Orbital and sinus rhabdomyosarcoma with concurrent central retinal artery occlusion: A case report. World J Clin Oncol 2024; 15(12): 1507-1513 [PMID: 39720648 DOI: 10.5306/wjco.v15.i12.1507]
Corresponding Author of This Article
Jing-Xiang Zhong, MD, Professor, Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, No. 88 Changdong Road, Changping, Dongguan 523000,Guangdong Province, China. zjx85221206@126.com
Research Domain of This Article
Ophthalmology
Article-Type of This Article
Case Report
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dec 24, 2024 (publication date) through Feb 13, 2026
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Journal Information of This Article
Publication Name
World Journal of Clinical Oncology
ISSN
2218-4333
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Ma Y, Jia B, He XJ, Cai YX, Chen JY, Zhong JX. Orbital and sinus rhabdomyosarcoma with concurrent central retinal artery occlusion: A case report. World J Clin Oncol 2024; 15(12): 1507-1513 [PMID: 39720648 DOI: 10.5306/wjco.v15.i12.1507]
Yu Ma, Bo Jia, Xiao-Juan He, Yue-Xia Cai, Jin-Ying Chen, Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou 510632, Guangdong Province, China
Jing-Xiang Zhong, Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, Dongguan 523000, Guangdong Province, China
Co-corresponding authors: Jin-Ying Chen and Jing-Xiang Zhong.
Author contributions: Ma Y drafted the manuscript; Ma Y, Chen JY, Jia B, He XJ and Cai YX gathered the clinical information, organized the data, conducted the clinical investigations, and coordinated the planning and execution of the study; All the authors have read and approved the final manuscript. As co-corresponding authors, Chen JY was involved in diagnosing and treating patients and conceived the manuscript's central idea, and Zhong JX oversaw the entire writing process and managed the manuscript submission. Chen JY and Zhong JX reviewed and revised the manuscript for accuracy and completeness. The collaborative efforts of Chen JY and Zhong JX were integral to the completion of the article.
Supported byNational Natural Science Foundation of China, No. 82271094; Science and Technology Projects in Guangzhou, No. 202201020030, No. 202201020015 and No. 202201010618; and Medical Scientific Research Foundation of Guangdong Province of China, No. A2022415.
Informed consent statement: The patient has provided informed consent, granting permission for the author to publish this case and accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Corresponding author: Jing-Xiang Zhong, MD, Professor, Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, No. 88 Changdong Road, Changping, Dongguan 523000,Guangdong Province, China. zjx85221206@126.com
Received: July 18, 2024 Revised: September 5, 2024 Accepted: September 30, 2024 Published online: December 24, 2024 Processing time: 95 Days and 23 Hours
Abstract
BACKGROUND
Both rhabdomyosarcoma (RMS) and central retinal artery occlusion (CRAO) are rare medical diseases, and their simultaneous occurrence in the same patient is extraordinarily uncommon. This study presents a comprehensive overview of the clinical manifestations, diagnostic imaging results, and therapeutic interventions of a patient with both conditions.
CASE SUMMARY
In this report, we present a 30-year-old male who presented with significant protrusion, pain and vision loss and was diagnosed with RMS in the orbit and sinus with CRAO. Following resection of the sinus and orbital mass and enucleation of the right eye, the patient experienced symptom improvement.
CONCLUSION
This article provides an in-depth analysis of the patient’s clinical manifestations, the tumor’s anatomical origin, and the etiology of CRAO. The concurrent manifestation of both RMS and CRAO is exceedingly uncommon in clinical practice.
Core Tip: Rhabdomyosarcoma is a highly malignant tumor that rarely occurs in young adults. We report a case of a 30-year-old male diagnosed with rhabdomyosarcoma involving the orbit and sinus complicated by central retinal artery occlusion. We investigated the causes of these conditions in this patient using the clinical presentation and signs, pathologic examination and imaging.