Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Dec 24, 2024; 15(12): 1507-1513
Published online Dec 24, 2024. doi: 10.5306/wjco.v15.i12.1507
Orbital and sinus rhabdomyosarcoma with concurrent central retinal artery occlusion: A case report
Yu Ma, Bo Jia, Xiao-Juan He, Yue-Xia Cai, Jin-Ying Chen, Jing-Xiang Zhong
Yu Ma, Bo Jia, Xiao-Juan He, Yue-Xia Cai, Jin-Ying Chen, Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou 510632, Guangdong Province, China
Jing-Xiang Zhong, Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, Dongguan 523000, Guangdong Province, China
Co-corresponding authors: Jin-Ying Chen and Jing-Xiang Zhong.
Author contributions: Ma Y drafted the manuscript; Ma Y, Chen JY, Jia B, He XJ and Cai YX gathered the clinical information, organized the data, conducted the clinical investigations, and coordinated the planning and execution of the study; All the authors have read and approved the final manuscript. As co-corresponding authors, Chen JY was involved in diagnosing and treating patients and conceived the manuscript's central idea, and Zhong JX oversaw the entire writing process and managed the manuscript submission. Chen JY and Zhong JX reviewed and revised the manuscript for accuracy and completeness. The collaborative efforts of Chen JY and Zhong JX were integral to the completion of the article.
Supported by National Natural Science Foundation of China, No. 82271094; Science and Technology Projects in Guangzhou, No. 202201020030, No. 202201020015 and No. 202201010618; and Medical Scientific Research Foundation of Guangdong Province of China, No. A2022415.
Informed consent statement: The patient has provided informed consent, granting permission for the author to publish this case and accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read CARE Checklist (2016), and the manuscript was prepared and revised according to CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jing-Xiang Zhong, MD, Professor, Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, No. 88 Changdong Road, Changping, Dongguan 523000,Guangdong Province, China. zjx85221206@126.com
Received: July 18, 2024
Revised: September 5, 2024
Accepted: September 30, 2024
Published online: December 24, 2024
Processing time: 95 Days and 23 Hours
Abstract
BACKGROUND

Both rhabdomyosarcoma (RMS) and central retinal artery occlusion (CRAO) are rare medical diseases, and their simultaneous occurrence in the same patient is extraordinarily uncommon. This study presents a comprehensive overview of the clinical manifestations, diagnostic imaging results, and therapeutic interventions of a patient with both conditions.

CASE SUMMARY

In this report, we present a 30-year-old male who presented with significant protrusion, pain and vision loss and was diagnosed with RMS in the orbit and sinus with CRAO. Following resection of the sinus and orbital mass and enucleation of the right eye, the patient experienced symptom improvement.

CONCLUSION

This article provides an in-depth analysis of the patient’s clinical manifestations, the tumor’s anatomical origin, and the etiology of CRAO. The concurrent manifestation of both RMS and CRAO is exceedingly uncommon in clinical practice.

Keywords: Rhabdomyosarcoma; Alveolar; Orbital tumor; Central retinal artery occlusion; Vision loss; Case report

Core Tip: Rhabdomyosarcoma is a highly malignant tumor that rarely occurs in young adults. We report a case of a 30-year-old male diagnosed with rhabdomyosarcoma involving the orbit and sinus complicated by central retinal artery occlusion. We investigated the causes of these conditions in this patient using the clinical presentation and signs, pathologic examination and imaging.