Published online Apr 24, 2022. doi: 10.5306/wjco.v13.i4.303
Peer-review started: November 25, 2021
First decision: January 12, 2022
Revised: January 20, 2022
Accepted: March 27, 2022
Article in press: March 27, 2022
Published online: April 24, 2022
Processing time: 148 Days and 0.1 Hours
Solitary fibrous tumors are rare neoplasms of mesenchymal origin. They are often of low malignant potential and rarely metastasize. They frequently arise from the pleura and can occur at any soft tissue site in the body. However, these tumors rarely develop in the mesentery, peritoneal cavity or peritoneum.
We report on a scarce case of solitary fibrous tumor of the rectal mesentery showing sarcomatosis about 4 years after previous tumor resection. This 69-year-old male had no clinical symptoms but was transferred to our hospital because of a suspected tumor recurrence from follow-up abdominal computed tomography. Tumor markers (CEA, CA 19-9 and CA 125) were within the normal range. Open laparotomy showed sarcomatosis, and pathology confirmed its mesenchymal origin and diagnosis as the solitary fibrous tumor. Our case may be the second recurrent mesentery solitary fibrous tumor reported to date, and the only one with progression to sarcomatosis. There has been no evidence of recurrence in follow-up at the 28th mo after extensive intra-operative peritoneal lavage and cytoreductive surgery.
Although there are few risk factors of cancer recurrence in this patient, careful long-term follow-up after cytoreductive surgery is necessary.
Core Tip: Solitary fibrous tumors (SFTs) are mostly benign and they rarely develop in the mesentery and cause sarcomatosis. The favored treatment strategy is whole-tumor excision with continued follow-up. According to a literature review, our patient is the first case report of mesentery SFT with the presentation of postoperative intraperitoneal recurrence and sarcomatosis.