Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Dec 24, 2020; 11(12): 1064-1069
Published online Dec 24, 2020. doi: 10.5306/wjco.v11.i12.1064
Latent brain infection with Moraxella osloensis as a possible cause of cerebral gliomatosis type 2: A case report
Tadej Strojnik, Rajko Kavalar, Kristina Gornik-Kramberger, Maja Rupnik, Slavica Lorencic Robnik, Mara Popovic, Tomaz Velnar
Tadej Strojnik, Department of Neurosurgery, University Medical Centre Maribor, Maribor SI-2000, Slovenia
Tadej Strojnik, Maja Rupnik, Faculty of Medicine, University of Maribor, Maribor SI-2000, Slovenia
Rajko Kavalar, Kristina Gornik-Kramberger, Department of Pathology, University Medical Centre Maribor, Maribor SI-2000, Slovenia
Maja Rupnik, Slavica Lorencic Robnik, National Laboratory for Health, Environment and Food, Maribor SI-2000, Slovenia
Mara Popovic, Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana 1000, Slovenia
Tomaz Velnar, Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana 1000, Slovenia
Author contributions: Strojnik T, Kavalar R, Rupnik M, Robnik SL, Popovic M and Gornik-Kramberger K drafted the manuscript, assisted with data analysis, and performed statistical analysis; Strojnik T and Velnar T participated in the design and the oversight of the study; all authors read and approved the final manuscript.
Informed consent statement: The patient provided informed consent.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tomaz Velnar, MD, PhD, Department of Neurosurgery, University Medical Centre Ljubljana, Zaloska 7, Ljubljana 1000, Slovenia. tvelnar@hotmail.com
Received: March 31, 2020
Peer-review started: March 31, 2020
First decision: September 24, 2020
Revised: October 10, 2020
Accepted: November 4, 2020
Article in press: November 4, 2020
Published online: December 24, 2020
Processing time: 262 Days and 3 Hours
Abstract
BACKGROUND

The gram-negative aerobic bacterium Moraxella osloensis is an opportunistic pathogen in brain tissues.

CASE SUMMARY

The gram-negative aerobic bacterium Moraxella osloensis was isolated from a patient’s brain tissue during a stereotactic biopsy.

CONCLUSION

This is the first report of a brain tissue infection with Moraxella osloensis possibly causing brain gliomatosis.

Keywords: Moraxella osloensis; Brain infection; Cerebral gliomatosis; Stereotactic brain biopsy; Case report

Core Tip: The gram-negative aerobic bacterium Moraxella osloensis is an opportunistic pathogen and was isolated from a patient’s brain tissue during a stereotactic biopsy. This is the first report of a brain tissue infection with Moraxella osloensis, possibly causing brain gliomatosis.