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World J Gastrointest Pharmacol Ther. Mar 5, 2026; 17(1): 112588
Published online Mar 5, 2026. doi: 10.4292/wjgpt.v17.i1.112588
Figure 1
Figure 1 Interaction of liver clock with central clock and entraining factors. Central clock regulates liver clock by signaling through hormones. Liver clock regulates metabolism. Lack of synchronisation can lead to metabolic disorders. HPA: Hypothalamic pituitary adrenal; SCN: Suprachiasmatic nucleus.