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Surgical interventions in inflammatory bowel disease: Indications, techniques, outcomes, and future directions
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World Journal of Gastrointestinal Pharmacology and Therapeutics is an international, peer-reviewed, open-access academic journal dedicated to publishing original, high-quality research findings in the field of gastrointestinal pharmacology and therapeutics, including clinical, translational, and basic studies, as well as research involving artificial intelligence. The journal focuses on, but is not limited to, the following areas: Acid-related disorders, gastrointestinal disease, hepatic and biliary disorders, pancreatic disorders, pharmacokinetics, clinical pharmacology, therapeutics. Types of articles published by the journal include clinical study, basic study, case report, editorial, review, minireview, systematic review, meta-analysis, guidelines, and correspondence. All submissions undergo a rigorous and transparent peer-review process by at least two independent reviewers. Manuscripts are evaluated based on scientific rigor, originality, clinical relevance, and reproducibility, with particular attention to methodological robustness and data integrity. Constructive and timely feedback is provided to ensure the highest standards of scholarly communication. The journal adheres to the highest standards of publication ethics and editorial integrity, in accordance with the guidelines of the Committee on Publication Ethics, the International Committee of Medical Journal Editors, and the World Association of Medical Editors. To advance scientific discovery, promote evidence-based clinical practice, and foster innovation in gastrointestinal pharmacology and therapeutics, ultimately improving global health outcomes. We invite researchers, clinicians, and multidisciplinary experts worldwide to submit high-quality manuscripts and contribute to shaping the future of gastrointestinal pharmacological and therapeutic science. Submit an Article >>

2026 Published Issues
2 1
Editors-in-Chief
  • Emanuele Sinagra, PhD, (E-mail: emanuelesinagra83@googlemail.com) Gastroenterology and Endoscopy Unit, Fondazione Istituto Giuseppe Giglio, Cefalù 90015, Italy
Indexing/Abstracting
The WJGPT is now abstracted and indexed in PubMed, PubMed Central, Reference Citation Analysis, China Science and Technology Journal Database, and Superstar Journals Database.
Journal Metrics
There is currently no impact factor.
ISSN
2150-5349 (online)
Latest Manuscript Statistics
Received (503), Duration of Peer Review (24 days/Mean), Days from Submission to First Decision (39 days/Mean), Second Decision Time (36 days/Mean), Accepted (61.0%/Mean), Production Time (51 days/Mean), Time to Publication (182 days/Mean), and Rejected (25.0%/Mean).
Current Issue
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Contents Volume 17 Issue 2 June 5, 2026
Review
Beyond gluten-free diet: Novel therapeutic frontiers in celiac disease armamentarium
Sandeep K Mundhra, Rakesh K Kochhar 
World J Gastrointest Pharmacol Ther 17(2):114292. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.114292
Current approaches to disease severity and therapy effectiveness assessment in patients with inflammatory bowel disease
Alexandre Loktionov 
World J Gastrointest Pharmacol Ther 17(2):116608. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.116608
Minireviews
Evolving prokinetic therapy: New targets and therapeutic opportunities in gastrointestinal motility disorders
Omesh Goyal, Rishi Chowdhary, Tanisha Sehgal, Tanvi Joshi, Akshit Bhambri, Insiya Mohammed Rampurawala, Gurmanleen Singh Sohi, Arghadip Das, Kirti Arora, Ashita Rukmini Vuthaluru, Manjeet Kumar Goyal 
World J Gastrointest Pharmacol Ther 17(2):118616. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118616
Beyond intestinal failure: Expanding therapeutic frontiers of glucagon-like peptide-2 in gastrointestinal disease
Philippe Attieh, Dana Dabboussi, Wael Meraabi, Karam Karam, Rose Raymond Al Bacha, Bassam Abboud 
World J Gastrointest Pharmacol Ther 17(2):118861. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118861
Precision immunotherapy in oesophageal squamous cell carcinoma: Molecular pathogenesis and checkpoint inhibitor response prediction
Meer M Chisthi, Sindhu Viswanath, Krishnakumar G Kuttanchettiyar 
World J Gastrointest Pharmacol Ther 17(2):119778. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.119778
Case Control Study
Frequency and predictors of small intestinal bacterial overgrowth in acute pancreatitis
Chidanand Kumbar, Venkatesh Vaithiyam, Ravi Teja Reddy, Kartik Mehta, Aarushi Ahuja, Ajay Kumar, Ashok Dalal, Sanjeev Sachdeva 
World J Gastrointest Pharmacol Ther 17(2):118784. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118784
Fructose malabsorption associated with functional abdominal bloating: Case-control study
Arivarasan Kulandaivelu, Venkatesh Vaithiyam, Kartik Mehta, Ravi Teja Reddy, Aarushi Ahuja, Nikhil Sirohi, Ujjwal Sonika, Ashok Dalal, Ajay Kumar, Amarender Singh Puri, Sanjeev Sachdeva 
World J Gastrointest Pharmacol Ther 17(2):121264. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.121264
Retrospective Cohort Study
Right biopsy protocol for microscopic colitis: Reduced workload and carbon footprint while maintaining diagnostic accuracy
Edric Leung, Yasir Alshareefy, Conor Costigan, Sandeep Sihag, Sarah Delaney, Sarah O’Donnell, Niall Breslin, Anthony O’Connor, Barbara Ryan, Abdul Zaheer, Ion Cretu, Fintan O’Hara, Deirdre McNamara 
World J Gastrointest Pharmacol Ther 17(2):113874. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.113874
Metabolic dysfunction–associated steatotic liver disease and obstructive sleep apnea: A cohort analysis of prevalence and hepatic outcomes
Rishi Chowdhary, Geng-Qing Song, Manjeet Kumar Goyal, Ashita Rukmini Vuthaluru, Kirti Arora, Rahul Chowdhary, Megh Patel, Akash Batta, Thai-Hau Koo, Venkata Sunkesula, Rohit Goyal, Omesh Goyal 
World J Gastrointest Pharmacol Ther 17(2):118130. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118130
Clinical outcomes of upadacitinib dose escalation in inflammatory bowel disease: A single-center retrospective cohort study
Abigail Layton Ellington, Danielle Rambuss, Sarah Barbina, Maithili Chitnavis 
World J Gastrointest Pharmacol Ther 17(2):120059. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.120059
Prospective Study
Effect of cholecystectomy on liver fat and fibrosis in metabolic dysfunction-associated steatotic liver disease patients
Khellaf Amalou, Nassila Belal, Abdelghani Tibouk, Yasmine Ghedada, Rym Rekab, Sabrina Fadel, Nabil Debzi, Abderezak Bousloub 
World J Gastrointest Pharmacol Ther 17(2):114876. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.114876
Predictors of clinically significant complications after stoma reversal: A prospective analytical study
Rohit Sangwan, Himanshu Agrawal, Nitin Agarwal, Haleema Ather, Peeyush Kumar, Nikhil Gupta 
World J Gastrointest Pharmacol Ther 17(2):120325. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.120325
Randomized Controlled Trial
Low-cost dynamic fascial traction using serial Bogota bag tightening in open abdomen management: A prospective randomized study
Kamesh Balhara, Ashish Sikaria, Dinesh Saini, Himanshu Agrawal, Nikhil Gupta, Nitin Agarwal, Apoorva Mardi 
World J Gastrointest Pharmacol Ther 17(2):118848. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118848
Systematic Reviews
Surgical interventions in inflammatory bowel disease: Indications, techniques, outcomes, and future directions
Himanshu Agrawal, Nikhil Gupta 
World J Gastrointest Pharmacol Ther 17(2):118778. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118778
Correspondence
Letter to the Editor: Deciphering macrophage heterogeneity and optimizing probiotics via spatial multi-omics
Di Meng, Bin-Bin Zhang, Jia-Nan Zhao 
World J Gastrointest Pharmacol Ther 17(2):118195. Published online Jun 5, 2026. doi: 10.4292/wjgpt.v17.i2.118195
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