Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Nov 6, 2015; 6(4): 172-182
Published online Nov 6, 2015. doi: 10.4292/wjgpt.v6.i4.172
Published online Nov 6, 2015. doi: 10.4292/wjgpt.v6.i4.172
Diagnosis and therapy of non-variceal upper gastrointestinal bleeding
Erwin Biecker, Department of Gastroenterology, Zollernalb Klinikum, 72336 Balingen, Germany
Author contributions: Biecker E solely performed all the work of this manuscript.
Conflict-of-interest statement: The author has no conflict-of-interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Erwin Biecker, MD, PhD, Department of Gastroenterology, Zollernalb Klinikum, Tübinger Str. 30, 72336 Balingen, Germany. erwin.biecker@zollernalb-klinikum.de
Telephone: +49-7433-90922601 Fax: +49-7433-90922605
Received: March 3, 2015
Peer-review started: March 5, 2015
First decision: April 29, 2015
Revised: May 10, 2015
Accepted: September 28, 2015
Article in press: October 9, 2015
Published online: November 6, 2015
Processing time: 250 Days and 15.3 Hours
Peer-review started: March 5, 2015
First decision: April 29, 2015
Revised: May 10, 2015
Accepted: September 28, 2015
Article in press: October 9, 2015
Published online: November 6, 2015
Processing time: 250 Days and 15.3 Hours
Core Tip
Core tip: Non-variceal upper gastrointestinal bleeding (UGIB) is still accompanied by a significant mortality rate in older patients. Causes of UGIB are ulcers, Mallory-Weiss lesions, erosions, esophagitis or angiodysplasia. Endoscopy offers the localisation of the bleeding site as well as a variety of therapeutic measures. Patients with peptic lesions are effectively treated with proton pump inhibitors. Helicobacter pylori is a risk factor for the genesis of peptic ulcers and eradication therapy should be given if it is present.