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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Mar 5, 2026; 17(1): 112825
Published online Mar 5, 2026. doi: 10.4292/wjgpt.v17.i1.112825
Published online Mar 5, 2026. doi: 10.4292/wjgpt.v17.i1.112825
Impact of Endocuff addition to real-time computer-aided detection of colorectal neoplasia in a randomised tandem colonoscopy trial
Ioannis Stasinos, Department of Gastroenterology, 417 Army Equity Fund Hospital (NIMTS), Athens 11528, Attikí, Greece
Theodoros Voulgaris, Theodosios A Theodosopoulos, Georgios P Karamanolis, Department of Endoscopy, 2nd Academic Surgical Unit, National and Kapodistrian University of Athens, Aretaieion Hospital, Athens 11528, Attikí, Greece
Ioannis A Kouimtsidis, Sofia A Zantza, Fwteini A Leventaki, Periklis A Apostolopoulos, Depart
John Vlachogiannakos, Department of Gastroenterology, School of Medicine, National and Kapodistrian University of Athens, Athens 11527, Attikí, Greece
Author contributions: Stasinos I finalized the manuscript; Stasinos I and Voulgaris T wrote the initial draft; Stasinos I and Apostolopoulos PA performed colonoscopy procedures; Stasinos I, Voulgaris T, Kouimtsidis IA, Zantza SA, and Leventaki FA were implicated in data collection; Theodosopoulos TA, Vlachogiannakos J, Apostolopoulos PA, and Karamanolis GP reviewed the manuscript. All authors have read and approved the final manuscript.
Institutional review board statement: A formal ethical approval was received by the Research and Ethics Committee of Aretaieion University Hospital (approval No. 489/14-03-2023).
Clinical trial registration statement: This study is registered at ClinicalTrials.gov. The registration identification number is 26847/21.03.2023.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: Data are available upon request. Readers may contact the corresponding author to request underlying data.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Theodoros Voulgaris, MD, PhD, Department of Endoscopy, 2nd Aca
Received: August 7, 2025
Revised: September 8, 2025
Accepted: November 26, 2025
Published online: March 5, 2026
Processing time: 188 Days and 18.2 Hours
Revised: September 8, 2025
Accepted: November 26, 2025
Published online: March 5, 2026
Processing time: 188 Days and 18.2 Hours
Core Tip
Core Tip: Adenoma detection rate (ADR) is associated with a decreased risk of developing interval colorectal cancer, whereas the adenoma miss rate during colonoscopy is related to the risk of post-colonoscopy colorectal cancer. Artificial in