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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Dec 5, 2025; 16(4): 110559
Published online Dec 5, 2025. doi: 10.4292/wjgpt.v16.i4.110559
Published online Dec 5, 2025. doi: 10.4292/wjgpt.v16.i4.110559
Trends in diverticular disease mortality among United States adults (1999–2020) by gender, race, and geographic region
Umar Maqbool, Department of General Surgery, King Edward Medical University, Lahore 54000, Pakistan
Muhammad Ahmad Raza, Department of General Surgery, Quaid-e-Azam Medical College, Bahawalpur 06318, Pakistan
Abdullah Maqbool, Department of General Surgery, Rashid Latif Medical College, Lahore 54000, Pakistan
Sanjay Chaudhri, Department of General Surgery, Leicester General Hospital, Leicester LE5 4PW, United Kingdom
Franscois Runau, Department of General Surgery, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom
Author contributions: Maqbool U, Raza MA, and Maqbool A contributed to the analysis and drafting of the manuscript; Chaudhri S and Runau F contributed to conceptualizing the study design, writing the draft, and reviewing it.
Institutional review board statement: No IRB approval was required for this article as it contains de-identified patient data from CDC WONDER database.
Informed consent statement: No informed consent was required for this article as it contains de-identified patient data from CDC WONDER database.
Conflict-of-interest statement: The authors report no personal, financial, political, or intellectual conflict of interest.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Franscois Runau, Department of General Surgery, Leicester Royal Infirmary, Infirmary Square, Leicester LE1 5WW, United Kingdom.
Received: June 11, 2025
Revised: July 15, 2025
Accepted: November 4, 2025
Published online: December 5, 2025
Processing time: 179 Days and 19.6 Hours
Revised: July 15, 2025
Accepted: November 4, 2025
Published online: December 5, 2025
Processing time: 179 Days and 19.6 Hours
Core Tip
Core Tip: There is limited comprehensive data on mortality rates due to diverticular disease. This study aims to investigate the mortality trends of diverticular disease over a two-decade period through demographic and regional stratification. Overall mortality has decreased over two decades; however, females and non-Hispanic whites have higher mortality rates. The study also identifies states and regions showing higher mortality rates. The study suggests that further research is necessary to identify the factors contributing to demographic and regional disparities in mortality, thereby enhancing public health measures for vulnerable populations.