Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Jul 5, 2022; 13(4): 57-66
Published online Jul 5, 2022. doi: 10.4292/wjgpt.v13.i4.57
Overweight and abdominal fat are associated with normal bone mineral density in patients with ulcerative colitis
Mirella Brasil Lopes, Andre Castro Lyra, Raquel Rocha, Fernanda Gomes Coqueiro, Carla Andrade Lima, Carolina Cunha de Oliveira, Genoile Oliveira Santana
Mirella Brasil Lopes, Andre Castro Lyra, Carla Andrade Lima, Genoile Oliveira Santana, Programa de Pós-graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador 40110-060, Brazil
Raquel Rocha, Fernanda Gomes Coqueiro, Departamento Ciências da Nutrição, Universidade Federal da Bahia, Salvador 40110-060, Brazil
Carolina Cunha de Oliveira, Departamento de Nutrição, Universidade Federal de Sergipe, Lagarto 49060-110, Brazil
Genoile Oliveira Santana, Departamento Ciências da Vida, Universidade do Estado da Bahia, Salvador 41.150-000, Brazil
Author contributions: Lopes MB, Rocha R, Coqueiro FG, and Santana GO designed the research; Lopes MB, Coqueiro FG, and Lima CA performed the research; Lopes MB, Rocha R, and de Oliveira CC analyzed the data; Lopes MB, Lyra AC, Rocha R, and Santana GO wrote the paper.
Institutional review board statement: The Ethics Committee of the University Hospital Professor Edgar Santos approved the study protocol (nº117/2011).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at raquelrocha2@yahoo.com.br. Participants gave informed consent for data sharing. No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Raquel Rocha, DSc, MSc, Academic Research, Adjunct Associate Professor, Ciências da Nutrição, Universidade Federal da Bahia, Avenida Araújo Pinho, 32, Salvador 40110-060, Brazil. raquelrocha2@yahoo.com.br
Received: January 28, 2022
Peer-review started: January 28, 2022
First decision: March 10, 2022
Revised: April 27, 2022
Accepted: May 28, 2022
Article in press: May 28, 2022
Published online: July 5, 2022
Processing time: 153 Days and 7.8 Hours
Core Tip

Core Tip: There is a high prevalence of osteopenia/osteoporosis in adult outpatients with ulcerative colitis in remission. Patients with ulcerative colitis had a 22.4 times greater chance of developing reduced bone mineral density than healthy individuals. Lower values of body mass index and body fat indicators were identified in patients with ulcerative colitis with low bone mineral density. Low bone mineral density was associated with males and those without excess weight and with normal waist circumference.