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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Pathophysiol. Mar 22, 2026; 17(1): 118294
Published online Mar 22, 2026. doi: 10.4291/wjgp.v17.i1.118294
Clinical significance of a possible route of transmission of Candida and Helicobacter pylori associations in gastroduodenal pathology
Sergey M Kotelevets
Sergey M Kotelevets, Department of Propaedeutics of Internal Medicine, North Caucasus State Academy, Cherkessk 369000, Russia
Author contributions: Kotelevets SM contributed to this paper, designed the overall concept and outline of the manuscript, contributed to the design of the manuscript, contributed to the writing, and editing the manuscript, illustrations, and review of literature.
Conflict-of-interest statement: The author declares that they have no conflict of interest.
Corresponding author: Sergey M Kotelevets, MD, Professor, Department of Propaedeutics of Internal Medicine, North Caucasus State Academy, Stavropolskaya Street 36, Cherkessk 369000, Russia. smkotelevets@mail.ru
Received: December 29, 2025
Revised: January 31, 2026
Accepted: March 3, 2026
Published online: March 22, 2026
Processing time: 81 Days and 19.9 Hours
Core Tip

Core Tip: The phenomenon of fungal and bacterial associations is of significant interest for understanding gastric carcinogenesis. Representatives of the human microbiota can be etiological factors for various diseases. The most common are Helicobacter pylori (H. pylori) and Candida. The Candida-Helicobacter association is a poorly studied problem, although its significant role in the development of gastroduodenal pathology is not in doubt. Currently, there is insufficient understanding of the transmission pathways of H. pylori infection. Of great interest are polymicrobial extragastroduodenal foci of infections associated with H. pylori, in particular in the oral cavity, female birth canal, urinary tract. These issues require further investigation.