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Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pathophysiol. Sep 22, 2025; 16(3): 106014
Published online Sep 22, 2025. doi: 10.4291/wjgp.v16.i3.106014
Single-session endoscopic ultrasound-guided gallbladder drainage and biopsy in pancreatic cancer, obstructive jaundice, and acute cholecystitis: A case report
Filippo Antonini, Durante Donnarumma, Tiziana Buono, Salomone Di Saverio, Andrea Gardini
Filippo Antonini, Durante Donnarumma, Tiziana Buono, Department of Gastroenterology and Interventional Endoscopy, Ospedale Mazzoni, Ascoli Piceno 63100, Marche, Italy
Salomone Di Saverio, Department of Surgery, Ospedale Madonna del Soccorso, Ascoli Piceno 63074, Marche, Italy
Andrea Gardini, Department of Surgery, Ospedale Mazzoni, Ascoli Piceno 63100, Marche, Italy
Author contributions: Antonini F wrote this manuscript; Donnarumma D, Buono T, Di Saverio S, and Gardini A reviewed the manuscript; All authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Filippo Antonini, Department of Gastroenterology and Interventional Endoscopy, Ospedale Mazzoni, via degli Iris 1, Ascoli Piceno 63100, Marche, Italy. filippo.antonini@sanita.marche.it
Received: February 13, 2025
Revised: May 21, 2025
Accepted: August 13, 2025
Published online: September 22, 2025
Processing time: 218 Days and 11.4 Hours
Core Tip

Core Tip: The combination of endoscopic ultrasound (EUS)-guided fine needle biopsy and endoscopic retrograde cholangiopancreatography is well-documented in the literature. EUS-guided biliary drainage is an established alternative when endoscopic retrograde cholangiopancreatograph fails. EUS-guided gallbladder drainage is increasingly recognized as a valuable option for effective biliary decompression. When EUS-guided gallbladder drainage is used to alleviate jaundice, confirming cystic duct patency is essential to avoid suboptimal drainage. An 81-year-old patient with pancreatic head cancer, obstructive jaundice, and acute calculous cholecystitis had cystic duct patency successfully confirmed via EUS. This enabled a combined therapeutic approach that effectively resolved the cholecystitis and relieved the biliary obstruction.