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World J Gastrointest Pathophysiol. Mar 22, 2022; 13(2): 50-58
Published online Mar 22, 2022. doi: 10.4291/wjgp.v13.i2.50
Risk assessment of hepatitis E transmission through tissue allografts
Rafael Villalba, Vicente Mirabet
Rafael Villalba, Center for Blood Transfusion, Tissues and Cells, Córdoba 14004, Spain
Vicente Mirabet, Cell and Tissue Bank, Centro de Transfusión de Valencia, Valencia 46014, Spain
Author contributions: Villalba R and Mirabet V contributed equally to this work.
Conflict-of-interest statement: The authors declare no conflict of interest.
Corresponding author: Vicente Mirabet, PhD, Senior Scientist, Cell and Tissue Bank, Centro de Transfusión de Valencia, Avenida del Cid, 65-A, Valencia 46014, Spain. mirabet_vic@gva.es
Received: March 17, 2021
Peer-review started: March 17, 2021
First decision: May 1, 2021
Revised: May 6, 2021
Accepted: January 25, 2022
Article in press: January 25, 2022
Published online: March 22, 2022
Processing time: 362 Days and 3.8 Hours
Core Tip

Core Tip: This manuscript provide a novel perspective of the mode of transmission of hepatitis E virus (HEV). HEV is mainly transmitted via fecal-oral route, but in recent years other transmission routes have been reported, including blood-borne transmission. The processing of tissue allografts in duly accredited tissue banks provides safe and efficient products.