Luo J, Chen JD, Chen Q, Yue LX, Zhou G, Lan C, Li Y, Wu CH, Lu JQ. Contrast-enhanced ultrasound improved performance of breast imaging reporting and data system evaluation of critical breast lesions. World J Radiol 2016; 8(6): 610-617 [PMID: 27358689 DOI: 10.4329/wjr.v8.i6.610]
Corresponding Author of This Article
Qing Chen, BM, Department of Ultrasound, Sichuan Provincial People’s Hospital, No. 32 First Ring Road, Chengdu 610072, Sichuan Province, China. 1718686103@qq.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Clinical Trials Study
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Luo J, Chen JD, Chen Q, Yue LX, Zhou G, Lan C, Li Y, Wu CH, Lu JQ. Contrast-enhanced ultrasound improved performance of breast imaging reporting and data system evaluation of critical breast lesions. World J Radiol 2016; 8(6): 610-617 [PMID: 27358689 DOI: 10.4329/wjr.v8.i6.610]
World J Radiol. Jun 28, 2016; 8(6): 610-617 Published online Jun 28, 2016. doi: 10.4329/wjr.v8.i6.610
Contrast-enhanced ultrasound improved performance of breast imaging reporting and data system evaluation of critical breast lesions
Jun Luo, Ji-Dong Chen, Qing Chen, Lin-Xian Yue, Guo Zhou, Cheng Lan, Yi Li, Chi-Hua Wu, Jing-Qiao Lu
Jun Luo, Ji-Dong Chen, Qing Chen, Lin-Xian Yue, Guo Zhou, Cheng Lan, Department of Ultrasound, Sichuan Provincial People’s Hospital, Chengdu 610072, Sichuan Province, China
Yi Li, Chi-Hua Wu, Department of Breast Surgery, Sichuan Provincial People’s Hospital, Chengdu 610072, Sichuan Province, China
Jing-Qiao Lu, Department of Otolaryngology, School of Medicine, Emory University, Atlanta, GA 30322, United States
Author contributions: Luo J designed the research; Luo J, Chen JD, Chen Q, Yue LX, Zhou G, Lan C, LI Y and Wu CH performed the research; Lu JQ analyzed the data; Luo J wrote the paper.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Sichuan Provincial People’s Hospital.
Clinical trial registration statement: This registration policy only applies to a prospective study.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: None declared.
Data sharing statement: No data were created so no data are available.
Correspondence to: Qing Chen, BM, Department of Ultrasound, Sichuan Provincial People’s Hospital, No. 32 First Ring Road, Chengdu 610072, Sichuan Province, China. 1718686103@qq.com
Telephone: +86-28-87394616 Fax: +86-28-87394616
Received: November 18, 2015 Peer-review started: November 19, 2015 First decision: February 2, 2016 Revised: February 27, 2016 Accepted: April 21, 2016 Article in press: April 22, 2016 Published online: June 28, 2016 Processing time: 213 Days and 19.3 Hours
Core Tip
Core tip: Many published studies show that overdiagnosis is now a problem faced if the breast imaging reporting and data system (BI-RADS) category is used in clinical practice. Many patients underwent unnecessary biopsies even if the final pathological results were benign lesions. It seems that BI-RADS is not good enough and one of the reasons may be that there is no microvascular information. Contrast-enhanced ultrasound (CEUS) can give us this information. We tried to determine whether CEUS can improve the precision of the BI-RADS categorization. Our results showed that in all BI-RADS 4 lesions which were suggested as needing a biopsy, CEUS-based BI-RADS can decrease false positive biopsies and increase cancer-to-biopsy yield and that only 4.68% invasive cancers were misdiagnosed.
