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World J Radiol. Feb 28, 2026; 18(2): 116799
Published online Feb 28, 2026. doi: 10.4329/wjr.v18.i2.116799
Published online Feb 28, 2026. doi: 10.4329/wjr.v18.i2.116799
Functional connectivity alterations in patients with poststroke cognitive impairment: A resting-state functional magnetic resonance imaging study
Yun-Yun Tao, Ran Wang, Peng Zhang, Xiao-Hua Huang, Lin Yang, Interventional Medical Center, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Co-first authors: Yun-Yun Tao and Ran Wang.
Co-corresponding authors: Xiao-Hua Huang and Lin Yang.
Author contributions: Tao YY, Wang R, and Zhang P analyzed the data and wrote the manuscript; Tao YY and Wang R contributed equally to this article, they are the co-first authors of this manuscript; Huang XH and Yang L conceptualized the study, they contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors contributed to manuscript revision and provided approval of the final version of the manuscript to be published.
Supported by the Affiliated Hospital of North Sichuan Medical College, No. 2020ZD017 and No. 2020ZD008.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Affiliated Hospital of North Sichuan Medical College, approval No. 2020ER117-1.
Informed consent statement: All of the participants provided signed informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The original contributions presented in this study are included in the article. Further inquiries can be directed to the corresponding author.
Corresponding author: Lin Yang, MD, Interventional Medical Center, Department of Radio
Received: November 25, 2025
Revised: December 25, 2025
Accepted: January 9, 2026
Published online: February 28, 2026
Processing time: 96 Days and 3.1 Hours
Revised: December 25, 2025
Accepted: January 9, 2026
Published online: February 28, 2026
Processing time: 96 Days and 3.1 Hours
Core Tip
Core Tip: Cognitive impairment is a common functional impairment after stroke that seriously affects the quality of life of patients. The underlying neurobiological mechanisms of poststroke cognitive impairment (PSCI) remain unclear. This study aimed to investigate the changes in brain functional connectivity of patients with PSCI, which may help explore the neurobiological mechanisms of PSCI from a new perspective.