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Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Nov 28, 2025; 17(11): 113153
Published online Nov 28, 2025. doi: 10.4329/wjr.v17.i11.113153
Variations in the spatial relationship between the hyoid bone and the carotid arteries and their clinical significance
Nektaria Karangeli, George Triantafyllou, Panagiotis Papadopoulos-Manolarakis, Nikolaos-Achilleas Arkoudis, Georgios Velonakis, Alexandros Samolis, Maria Piagkou
Nektaria Karangeli, George Triantafyllou, Panagiotis Papadopoulos-Manolarakis, Alexandros Samolis, Maria Piagkou, Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens 11527, Attikí, Greece
George Triantafyllou, Maria Piagkou, “VARIANTIS” Research Laboratory, Department of Clinical Anatomy, Mazovian Academy in Płock, Płock 09-402, Poland
Panagiotis Papadopoulos-Manolarakis, Department of Neurosurgery, General Hospital of Nikaia-Piraeus, Athens 18454, Attikí, Greece
Nikolaos-Achilleas Arkoudis, Georgios Velonakis, Research Unit of Radiology and Medical Imaging, National and Kapodistrian University of Athens, Athens 11528, Greece
Nikolaos-Achilleas Arkoudis, Georgios Velonakis, Second Department of Radiology, General University Hospital “Attikon”, National and Kapodistrian University of Athens, Athens 12462, Chaidari, Greece
Co-corresponding authors: George Triantafyllou and Nikolaos-Achilleas Arkoudis.
Author contributions: Karangeli N was responsible for project development, data collection and management; Triantafyllou G contributed to conceptualization; Karangeli N, Triantafyllou G, Papadopoulos-Manolarakis P, Arkoudis NA, Velonakis G, Samolis A, and Piagkou M contributed to data analysis and manuscript writing; Maria Piagkou oversaw the project (supervision); Triantafyllou G and Arkoudis NA they contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of General Hospital of Nikaia-Piraeus, approval No. 56485.
Informed consent statement: Informed consent was obtained from the patients enrolled in the current study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All the data are available upon reasonable request to the authors.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nikolaos-Achilleas Arkoudis, MD, PhD, Research Unit of Radiology and Medical Imaging, National and Kapodistrian University of Athens, 19 Papadiamantopoulou, Athens 11528, Greece. nick.arkoudis@gmail.com
Received: August 18, 2025
Revised: September 3, 2025
Accepted: November 7, 2025
Published online: November 28, 2025
Processing time: 102 Days and 10.5 Hours
Core Tip

Core Tip: The spatial relationship between the hyoid bone and carotid arteries is highly variable and may predispose patients to vascular compression, stroke, or surgical complications. This retrospective computed tomography angiography-based study of 224 patients highlights common topographical variants, their sex-related distribution, and clinical implications. Recognition of these carotid-hyoid configurations in preoperative imaging can aid in preventing iatrogenic injury, improving diagnosis in cryptogenic cerebrovascular events, and guiding safer surgical planning.