Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Nov 28, 2025; 17(11): 111651
Published online Nov 28, 2025. doi: 10.4329/wjr.v17.i11.111651
Published online Nov 28, 2025. doi: 10.4329/wjr.v17.i11.111651
Shear wave elastography in healthy patients: Pancreatic stiffness is less reliable than liver and spleen measurements
Nicholas Viceconti, Mattia Paratore, Laura Riccardi, Matteo Garcovich, Diagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy
Fabio Del Zompo, Maria Assunta Zocco, Maria Elena Ainora, Giorgio Esposto, Antonio Gasbarrini, Internal Medicine and Gastroenterology Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Gemelli IRCCS, Rome 00168, Italy
Maria Assunta Zocco, Antonio Gasbarrini, Maurizio Pompili, Translational Medicine and Surgery Department, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Gemelli IRCCS, Rome 00168, Italy
Maurizio Pompili, Internal Medicine and Liver Transplantation Unit, Fondazione Policlinico Universitario Gemelli IRCCS, Rome 00168, Italy
Author contributions: Viceconti N, Garcovich M, Del Zompo F, Riccardi L, and Garcovich M contributed to conceptualization, investigation, and editing; Viceconti N and Garcovich M contributed to study design, supervision, writing the first draft, and review; Paratore M, Riccardi L, and Garcovich M contributed to acquisition, analysis, and interpretation of data; all authors revised the manuscript critically for intellectual content and approved the final version.
Institutional review board statement: This study was reviewed and approved by the Comitato Etico, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, No. 3584.
Informed consent statement: Each patient agreed to participate in the study by written informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: All participants’ personal data were anonymized before analysis, and data handling fully complied with the General Data Protection Regulation (EU) 2016/679 (GDPR) and applicable national privacy laws. The authors can provide datasets upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mattia Paratore, MD, Diagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Rome 00168, Italy.
Received: July 8, 2025
Revised: September 15, 2025
Accepted: November 6, 2025
Published online: November 28, 2025
Processing time: 142 Days and 11.4 Hours
Revised: September 15, 2025
Accepted: November 6, 2025
Published online: November 28, 2025
Processing time: 142 Days and 11.4 Hours
Core Tip
Core Tip: In the literature, normal stiffness values for liver, spleen, and pancreas in healthy individuals are not well established. This is partly due to differences in equipment and cut-off values used, and partly due to inter-operator variability. In this study, we evaluated these parameters in 50 healthy individuals using three different methods (two of which were integrated into the same scan) to assess their correlation with clinical and technical features.