Proteomics-based investigation of the protective effect and mechanism of Agari-5 in rats with myocardial infarction

doi:10.4330/wjc.v17.i12.112062

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Dec 26, 2025 (publication date) through Dec 24, 2025

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Cardiol. Dec 26, 2025; 17(12): 112062
Published online Dec 26, 2025. doi: 10.4330/wjc.v17.i12.112062

Table 1 Statistical table of differential protein expression

Gene	Agari5 vs model regulation	Model vs control regulation	Agari5 vs control regulation
Neb	Up	Down	Insig
Pnkp	Up	Down	Insig
Papss1	Up	Down	Insig
Lonrf1	Up	Down	Insig
Psat1	Down	Up	Insig
Ccser2	Up	Down	Insig
Man1c1	Down	Up	Insig
Smoc1	Down	Up	Insig
AC095947.1	Up	Down	Insig
Nxn	Up	Down	Insig
Tanc1	Up	Down	Insig
Sdf2	Up	Down	Insig
Syap1	Up	Down	Insig
Dmc1	Up	Down	Insig
Nom1	Up	Down	Insig
Decr1	Down	Up	Insig
Rnpep	Down	Up	Insig
Pdk1	Up	Down	Insig
Isg15	Up	Down	Insig
Trio	Up	Down	Insig
Trim32	Up	Down	Insig
Csnk2a2	Up	Down	Insig
Chgb	Up	Down	Insig
Cdk18	Down	Up	Insig
Pold1	Down	Up	Insig
Smad4	Up	Down	Insig
Otc	Up	Down	Insig
Mbp	Down	Up	Insig
Psbpc1	Down	Up	Insig
Ptprc	Up	Down	Insig
Grb10	Up	Down	Insig
Pth1r	Up	Down	Insig
Slc6a7	Down	Up	Insig
Vcam1	Down	Up	Insig
Map1a	Down	Up	Insig
Afm	Up	Down	Insig
Il6st	Up	Down	Insig
Padi3	Up	Down	Insig
Ermard	Down	Up	Insig
Gramd1a	Up	Down	Insig
Znf830	Down	Up	Insig
Lztfl1	Down	Up	Insig
Cep70	Down	Up	Insig
Armcx3	Up	Down	Insig
Synj1	Up	Down	Insig
Nrxn1	Down	Up	Insig
Prx	Down	Up	Insig
Ces1f	Down	Up	Insig
Isg20 L2	Up	Down	Insig
Dync2 Li1	Down	Up	Insig
Blvra	Up	Down	Insig
Krt42	Up	Down	Insig
Tepp	Down	Up	Insig
Fmo2	Up	Down	Insig
Wls	Up	Down	Insig
Rsl1d1 L1	Up	Down	Insig
Asrgl1	Down	Up	Insig
Ttl	Up	Down	Insig
Nme7	Down	Up	Insig
Pde4dip	Up	Down	Insig

Insig: Insignificant.

Full Size Table

Citation: Zhao YB, Bao ZH, Tu Y, Qiu X, Bao YL, Su M, Qi HJ, Wan Q. Proteomics-based investigation of the protective effect and mechanism of Agari-5 in rats with myocardial infarction. World J Cardiol 2025; 17(12): 112062
URL: https://www.wjgnet.com/1949-8462/full/v17/i12/112062.htm
DOI: https://dx.doi.org/10.4330/wjc.v17.i12.112062