Association of chronic periodontitis in a broad spectrum of cardiometabolic syndrome: A minireview

Core Tip

Core Tip: Cardiometabolic syndrome (CMS) plays a pivotal role in global increase in the incidence of cardiovascular disease (CVD) in the developing countries. The multi-organ insulin resistance appears to key driver of both metabolic syndrome and CVDs. The two most prevalent dental diseases i.e., periodontitis (PD) and dental caries have been related to several systemic diseases and disorders, such as CMS. Age, alcohol consumption, being obese, possessing diabetes, as well as smoking are risk factors for periodontal diseases and CVD alike. Periodontal diseases are intricately linked to systemic inflammation and are associated with many systemic diseases. When bacteria and their products attack the periodontal tissues, the tissue raises an immune-inflammatory response against the pathogens. This acute phase response is a result of the pathogen’s systemic attack and adds to the overall inflammatory burden of the system. CVD and PD are both diseases associated with systemic inflammation and may be related as they share many common risk factors. Hence, the correlation between these conditions might also have an impact on how dentistry and medicine are practised, thus helping to build a working relationship between the dentist and the physician.