Cai B, Qiao ML, Miao D, Liu GZ. Cardiac myxoma and its implications for cardioembolic stroke. World J Cardiol 2025; 17(12): 112396 [DOI: 10.4330/wjc.v17.i12.112396]
Corresponding Author of This Article
Guang-Zhi Liu, MD, PhD, Professor, Department of Neurology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, No. 33 Badachu Road, Shijingshan District, Beijing 100144, China. guangzhi2002@hotmail.com
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Neurosciences
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Minireviews
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dec 26, 2025 (publication date) through Dec 24, 2025
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World Journal of Cardiology
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1949-8462
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Cai B, Qiao ML, Miao D, Liu GZ. Cardiac myxoma and its implications for cardioembolic stroke. World J Cardiol 2025; 17(12): 112396 [DOI: 10.4330/wjc.v17.i12.112396]
World J Cardiol. Dec 26, 2025; 17(12): 112396 Published online Dec 26, 2025. doi: 10.4330/wjc.v17.i12.112396
Cardiac myxoma and its implications for cardioembolic stroke
Bin Cai, Man-Li Qiao, Dan Miao, Guang-Zhi Liu
Bin Cai, Guang-Zhi Liu, Department of Neurology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing 100144, China
Man-Li Qiao, Department of General Practice, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China
Dan Miao, Department of Neurology, Qingdao Hiser Hospital Affiliated of Qingdao University/Qingdao Traditional Chinese Medicine Hospital, Qingdao 266011, Shandong Province, China
Author contributions: Cai B was responsible for the initial draft, conceptualization, methodology, and project administration; Qiao ML contributed to investigation, and supervision; Qiao ML and Miao D participated in review and editing; Miao D participated in data curation, formal analysis, and validation; Liu GZ contributed to conceptualization, funding acquisition, and visualization; and all authors thoroughly reviewed and endorsed the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82071342.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guang-Zhi Liu, MD, PhD, Professor, Department of Neurology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, No. 33 Badachu Road, Shijingshan District, Beijing 100144, China. guangzhi2002@hotmail.com
Received: July 27, 2025 Revised: September 4, 2025 Accepted: November 13, 2025 Published online: December 26, 2025 Processing time: 152 Days and 1.6 Hours
Core Tip
Core Tip: Cardiac myxoma, although rare, is a significant cause of cardioembolic stroke in young adults, often due to embolism from tumor fragments or metastatic spread. The link between tumor mobility, morphology, and stroke risk remains unclear. This article explores the relationship between cardiac myxoma and ischemic stroke (CM-IS), highlighting two potential pathogenetic mechanisms and identifying tumor morphology and mobility as critical risk factors. CM-IS predominantly affects younger patients presenting with acute neurological symptoms, necessitating tailored diagnostic and therapeutic approaches. The analysis highlights the complexity of CM-IS and calls for further research to refine its management and support clinical decision making.
