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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Nov 26, 2025; 17(11): 113225
Published online Nov 26, 2025. doi: 10.4330/wjc.v17.i11.113225
Published online Nov 26, 2025. doi: 10.4330/wjc.v17.i11.113225
Interpreting fractional flow reserve-guided percutaneous coronary intervention vs coronary artery bypass grafting outcomes
Heng-Rui Liu, Department of Research, Yinuo Bio company, Tianjin 061102, China
Jie-Ling Weng, Department of Pathology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
Co-corresponding authors: Heng-Rui Liu and Jie-Ling Weng.
Author contributions: Liu HR and Weng JL wrote the paper; they contributed equally to this manuscript and are the corresponding authors.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Heng-Rui Liu, Department of Research, Yinuo Bio company, 1-1204, Shuchang Park, Wanxin Street, Dongli District, Tianjin 061102, China. lh@yinuobiomedical.cn
Received: August 19, 2025
Revised: August 27, 2025
Accepted: October 21, 2025
Published online: November 26, 2025
Processing time: 94 Days and 8.4 Hours
Revised: August 27, 2025
Accepted: October 21, 2025
Published online: November 26, 2025
Processing time: 94 Days and 8.4 Hours
Core Tip
Core Tip: This commentary highlights that although coronary artery bypass grafting remains superior to fractional flow reserve-guided percutaneous coronary intervention in reducing myocardial infarction and repeat revascularization in multivessel coronary artery disease, optimal outcomes may require an integrative approach. By combining revascularization with evidence-based traditional Chinese medicine to improve systemic vascular health and microcirculation, future strategies could transcend the dichotomy of “surgery vs stenting” and offer more durable, patient-centered benefits.