BPG is committed to discovery and dissemination of knowledge
Opinion Review
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Dec 26, 2025; 17(12): 112047
Published online Dec 26, 2025. doi: 10.4330/wjc.v17.i12.112047
Point-of-care ultrasound: Uniting cardiology and nephrology at the bedside
Nikitha C Chandra, Deepti Bhattacharya, Abhilash Koratala
Nikitha C Chandra, Division of Pulmonary, Allergy, and Sleep Medicine, Mayo Clinic, Jacksonville, FL 32224, United States
Deepti Bhattacharya, Department of Biology, Health and Environment, University of Texas at San Antonio, San Antonio, TX 78249, United States
Abhilash Koratala, Division of Nephrology, Medical College of Wisconsin, Milwaukee, WI 53226, United States
Author contributions: Chandra NC conducted the literature search and prepared the initial draft of the manuscript; Bhattacharya D carried out an independent literature search and contributed to manuscript revision; Koratala A reviewed and refined the manuscript for critical intellectual content.
Conflict-of-interest statement: The authors have no conflicts of interest to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abhilash Koratala, Associate Professor, Senior Researcher, Division of Nephrology, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI 53226, United States. akoratala@mcw.edu
Received: July 16, 2025
Revised: August 9, 2025
Accepted: November 12, 2025
Published online: December 26, 2025
Processing time: 161 Days and 14 Hours
Abstract

Cardiorenal syndrome reflects a complex interplay between cardiac and renal dysfunction, often compounded by fragmented management between cardiology and nephrology. Traditional phrases such as “the heart likes it dry and the kidneys like it wet” oversimplify care and perpetuate misconceptions about diuretic use and fluid management. Emerging evidence points to venous congestion rather than reduced cardiac output as a key driver of worsening renal function and adverse outcomes in heart failure. This article blends current evidence with the authors’ perspective and clinical experience to explore the role of point-of-care ultrasound (POCUS) in the hemodynamic assessment of cardiorenal dysfunction, highlighting practical frameworks and tools. Conventional bedside assessment tools are limited, and static markers such as serum creatinine and physical signs can be misleading. POCUS provides a dynamic, physiology-based evaluation by integrating focused cardiac imaging, venous Doppler, lung ultrasound, and abdominal views. Frameworks such as “pump, pipes, and leaks” and scoring systems like venous excess ultrasound enable real-time visualization and quantification of congestion, shifting practice from assumption-based to data-driven care and fostering alignment between specialties. As training opportunities expand and supporting evidence grows, POCUS should be regarded as a core clinical skill in the management of cardiorenal dysfunction, with the potential to improve diagnostic precision and guide targeted therapy.

Keywords: Ultrasound; Point-of-care ultrasound; Congestion; Cardiorenal; Venous excess ultrasound

Core Tip: Cardiorenal syndrome is often managed through conflicting specialty-specific approaches rooted in outdated assumptions about fluid status and creatinine trends. Emerging data emphasize venous congestion, not just reduced cardiac output, as a key driver of renal dysfunction. Traditional tools lack sensitivity and physiologic specificity. Point-of-care ultrasound (POCUS) offers a real-time, integrative method to assess forward flow, congestion, and extravascular fluid using focused cardiac, venous Doppler, and lung ultrasound. This physiology-based approach enables individualized care, clarifies rising creatinine during decongestion, and fosters consensus across specialties. POCUS should be seen not only as a tool but as a shared clinical language.