Association between type 2 diabetes mellitus and colorectal adenoma: A retrospective study with insights into Wnt/β-Catenin/TCF7L2 pathway activation

doi:10.4240/wjgs.v18.i2.113476

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 113476
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113476

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Figure 1 Ki67 staining assay for detecting proliferating cells. Hematoxylin-stained nuclei are blue, and diaminobenzidine-positive is brownish yellow.

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Figure 2 β-catenin presence detected with immunohistochemistry. Hematoxylin-stained nuclei are blue, and diaminobenzidine-positive is brownish yellow.

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Figure 3 Transcription factor 7 like 2 presences detected with immunohistochemistry. Hematoxylin-stained nuclei are blue, and diaminobenzidine-positive is brownish yellow.

Citation: Gui SY, Tang RX, Huang X, Yang GQ, Yang J. Association between type 2 diabetes mellitus and colorectal adenoma: A retrospective study with insights into Wnt/β-Catenin/TCF7L2 pathway activation. World J Gastrointest Surg 2026; 18(2): 113476
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/113476.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.113476