Impact of teduglutide on pediatric short bowel syndrome: A systematic review and trial sequential meta-analysis

doi:10.4240/wjgs.v17.i12.112685

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Dec 27, 2025 (publication date) through Dec 25, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Gastrointest Surg. Dec 27, 2025; 17(12): 112685
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.112685

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Figure 1 The flowchart of the screening process and results.

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Figure 2 The plot of the risk of bias.

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Figure 3 Forest plots for the association between teduglutide and safety outcomes in pediatric short bowel syndrome patients. A: Infection events; B: Upper respiratory tract infection; C: Catheter site infection; D: Vomiting; E: Abdominal pain; F: Nausea; G: Diarrhea; H: Abdominal distension.

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Figure 4 Trial sequential analysis of incidence of infection events.

Citation: Jiao P, Zhang ZJ, Jiang Y, Zhou J, Deng KH, Zhu WX, Zhao XY, Guo ZK. Impact of teduglutide on pediatric short bowel syndrome: A systematic review and trial sequential meta-analysis. World J Gastrointest Surg 2025; 17(12): 112685
URL: https://www.wjgnet.com/1948-9366/full/v17/i12/112685.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i12.112685