Impact of primary colorectal cancer site on surgical outcomes for liver metastases: A retrospective study

Figure 1 Analysis of risk factors. A: Postoperative recurrence in patients with liver metastases from colorectal cancer. The forest plot displays odds ratios (OR) and 95% confidence intervals (CI) for six independent risk factors identified through multivariate logistic regression analysis in 178 patients. The vertical dashed line represents OR = 1.0 (no effect). Data points (circles) represent OR values with horizontal lines indicating 95%CI. All factors showed statistically significant associations with increased recurrence risk (P < 0.05); B: Correlation analysis between primary location and risk factors for colorectal cancer. Analysis of the correlation between different factors and lymph node metastasis. The figure shows the correlation coefficients (r) values between D-dimer, albumin, neoadjuvant chemotherapy efficacy, and clinical risk score with lymph node metastasis. D-dimer has a strong positive correlation with lymph node metastasis (r = 0.86), while neoadjuvant chemotherapy efficacy has a negative correlation with lymph node metastasis (r = -0.54). The correlation between albumin and clinical risk score with lymph node metastasis is relatively weak.

Figure 2 Impact of primary site. A: Postoperative recurrence of colorectal cancer in patients with different primary tumor locations. Distribution of case numbers in the left colon, right hemicolon, and rectum at different time points. The bar chart illustrates the number of cases in the left colon, right hemicolon, and rectum at 3 months, 6 months, and 12 months. It is observed that the number of cases in the right hemicolon is significantly higher at 12 months compared to other locations and time points, while the case numbers in the left colon and rectum are relatively similar across the three time points; B: Impact of primary site on overall survival and disease-free survival. Blue bars represent overall survival and green bars represent disease-free survival. Right-sided colon cancer patients demonstrated significantly shorter overall survival and disease-free survival compared to left-sided colon and rectal cancer patients.