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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Apr 27, 2026; 18(4): 118338
Published online Apr 27, 2026. doi: 10.4240/wjgs.v18.i4.118338
Effects of perioperative nutritional status on the gastrointestinal anastomosis: A narrative review
Ray Salameh, Peter Samuel, Bhavya Virmani, Farah Ghobar, Lea Nohra, Marsel Khaddaj, Ranjith Kumar
Ray Salameh, Department of General Surgery, Lebanese American University, Achrafieh 1100, Lebanon
Peter Samuel, Ranjith Kumar, Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia
Bhavya Virmani, Department of General Surgery, New Civil Hospital, Surat 395001, Gujarāt, India
Farah Ghobar, Department of Surgery, University of Balamand, Beirut 3852, Beirut, Lebanon
Lea Nohra, Faculty of Medicine, Lebanese University, Beirut 2050, Lebanon
Marsel Khaddaj, Faculty of Medicine, Beirut Arab University, Beirut 2050, Beirut, Lebanon
Co-corresponding authors: Ray Salameh and Bhavya Virmani.
Author contributions: Salameh R, Samuel P, and Virmani B conceptualized the proposal, article, and study design; Salameh R and Samuel P performed the data acquisition; Salameh R, Samuel P, Virmani B, Ghobar F, Nohra L, Khaddaj M, and Kumar R conducted the data analysis and drafted the article; Salameh R and Virmani B provided critical revision of the article for important intellectual content and approved the final version for publication, and as such their collaborative contributions are critical to the publication of this paper and to the ongoing nature of the project, underlying their designation as co-corresponding authors.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Ray Salameh, MD, Department of General Surgery, Lebanese American University, Zahar Street, Achrafieh 1100, Lebanon. ray.salameh@lau.edu
Received: January 28, 2026
Revised: March 5, 2026
Accepted: April 2, 2026
Published online: April 27, 2026
Processing time: 115 Days and 16.6 Hours
Core Tip

Core Tip: This study evaluated the outcomes of perioperative nutritional status on the gastrointestinal anastomosis along the different anatomical places where it can be created, exploring the different complications that arise in cases of malnutrition such as wound dehiscence, anastomotic leakage, surgical site infections, and ways to improve outcomes through a multidisciplinary approach mainly by implementing early enteral nutrition as well as the emerging concept of using probiotics.