©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Feb 27, 2026; 18(2): 114137
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114137
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114137
Colitis cystica profunda diagnosed by laparoscopic excision: A case report and review of literature
Tong Zhao, Xian-Ru Jia, Kai-Jiang Li, Wen-Feng Zheng, Xue-Jin Liu, Department of Gastroenterology, Zhoukou Central Hospital Affiliated to Henan Medical University, Zhoukou 466000, Henan Province, China
Co-first authors: Tong Zhao and Xian-Ru Jia.
Author contributions: Zhao T and Jia XR contributed to manuscript writing and editing, and data collection, and they contributed equally to this manuscript and are co-first authors; Zhao T, Li KJ and Zheng WF contributed to data analysis; Liu XJ contributed to conceptualization and supervision. All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Xue-Jin Liu, MD, Chief Physician, Director, Department of Gastroen
Received: September 15, 2025
Revised: November 11, 2025
Accepted: December 29, 2025
Published online: February 27, 2026
Processing time: 165 Days and 19.3 Hours
Revised: November 11, 2025
Accepted: December 29, 2025
Published online: February 27, 2026
Processing time: 165 Days and 19.3 Hours
Core Tip
Core Tip: Colitis cystica profunda is a rare, benign but easily misdiagnosed cystic mucin-filled lesion that favors the recto-sigmoid wall, may be clinically silent or masquerade as mucinous neoplasm, and can only be confidently distinguished from malignancy by histopathologic examination of the fully excised specimen, so complete surgical removal and thorough pathologic assessment remain the cornerstone of management.