©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Feb 27, 2026; 18(2): 113103
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113103
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113103
Two-port vs four-port laparoscopic resection for colorectal cancer: Efficacy and outcomes
Hong-Xing Xia, Department of Gastrointestinal Surgery, Affiliated Nanhua Hospital, University of South China, Hengyang 421001, Hunan Province, China
Su Peng, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of University of South China, Hengyang 421001, Hunan Province, China
Author contributions: Xia HX performed the study conceptualization and design, data interpretation, statistical analysis, and manuscript preparation, drafted the initial manuscript, and reviewed and revised the paper; Peng S contributed to data quality assessment; Xia HX and Peng S contributed to data acquisition; all authors have read and agreed to the published version of the manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of the Second Affiliated Hospital of University of South China.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Data sharing statement: No additional data are available.
Corresponding author: Su Peng, MD, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of University of South China, No. 35 Jiefang Avenue, Hengyang 421001, Hunan Province, China. pengsu1234@126.com
Received: September 16, 2025
Revised: November 6, 2025
Accepted: December 10, 2025
Published online: February 27, 2026
Processing time: 162 Days and 22.1 Hours
Revised: November 6, 2025
Accepted: December 10, 2025
Published online: February 27, 2026
Processing time: 162 Days and 22.1 Hours
Core Tip
Core Tip: This study compares the efficacy of two-port with that of four-port laparoscopic radical resection of colorectal cancer. The two-port approach shows clinical superiority, with reduced total incision length, quicker postoperative recovery, fewer total complications, and better gastrointestinal/humoral immune functions. The results can provide better surgical treatment options for patients with colorectal cancer.