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World J Gastrointest Surg. Feb 27, 2026; 18(2): 112776
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.112776
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.112776
Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions
Ying Ling, Jun Wang, Chun-Hui Xi, Juan Liu, Digestive Endoscopy Center, Department of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Ying Ling, Jun Wang, Chun-Hui Xi, Juan Liu, Sichuan Branch of National Clinical Research Center for Digestive Diseases, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Author contributions: Ling Y and Liu J were involved in the conception, design, analysis, and interpretation of the data; Wang J contributed to drafting of the paper, revising it critically for intellectual content; Xi CH contributed to the final approval of the version to be published. All authors agree to be accountable for all aspects of the work.
Institutional review board statement: This study was approved by the Medicine Ethics Committee of Affiliated Hospital of North Sichuan Medical College.
Informed consent statement: Informed consent was waived because the research involved retrospective analysis of anonymized data and posed no risk to patients, in accordance with ethical guidelines for retrospective studies.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Corresponding author: Juan Liu, Associate Chief Physician, Digestive Endoscopy Center, Department of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan South Road, Shunqing District, Nanchong 637000, Sichuan Province, China.
Received: September 23, 2025
Revised: October 27, 2025
Accepted: December 11, 2025
Published online: February 27, 2026
Processing time: 155 Days and 23.3 Hours
Revised: October 27, 2025
Accepted: December 11, 2025
Published online: February 27, 2026
Processing time: 155 Days and 23.3 Hours
Core Tip
Core Tip: This study compared endoscopic submucosal dissection and conventional gastrectomy in 206 patients with early gastrointestinal lesions. The findings demonstrate endoscopic submucosal dissection significant clinical advantages, including reduced intraoperative bleeding, shorter operative time, and faster postoperative recovery. This study carries clinical implications, establishing endoscopic submucosal dissection as a preferred treatment option that can significantly reduce surgical trauma, shorten the perioperative process, and promote the rapid recovery of patients with early gastrointestinal lesions.