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Retrospective Study
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2026; 18(1): 112988
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.112988
Comparison of epidural anesthesia and intravenous self-control analgesia on postoperative recovery quality in duodenectomy
Pan-Pan Li, Qiang Qu, Chang-Hui Shao
Pan-Pan Li, School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, Sichuan Province, China
Qiang Qu, Department of Anesthesiology, Hospital of Chengdu University of Traditional Chinese Medicine, Traditional Chinese Medicine Hospital of Sichuan Province, Chengdu 610032, Sichuan Province, China
Chang-Hui Shao, Department of Anesthesiology, Chengdu Integrated Traditional Chinese and Western Medicine Hospital (Chengdu First People’s Hospital), Chengdu 610000, Sichuan Province, China
Author contributions: Li PP contributed to conceptualization, statistical analysis, manuscript drafting, and revision; Qu Q contributed to study design, patient recruitment, critical review of manuscript content, and final approval; Shao CH contributed to study conception and design, supervision and analysis, critical revision of manuscript for important intellectual content, and final approval. All authors have contributed to data collection, read and approved the final manuscript, and agree to be accountable for all aspects of the work.
Institutional review board statement: This study was approved by the Ethics Committee of Chengdu Integrated Traditional Chinese and Western Medicine Hospital (Chengdu First People’s Hospital) (No. 2025KT010).
Informed consent statement: This study was conducted as a retrospective analysis of anonymized clinical data. No identifiable personal information was collected or used. Given the study’s retrospective design and the use of de-identified data, the requirement for signed informed consent was formally waived by the Ethics Committee of Chengdu Integrated Traditional Chinese and Western Medicine Hospital (No. 2025KT010).
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets generated and/or analyzed during the present study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chang-Hui Shao, Department of Anesthesiology, Chengdu Integrated Traditional Chinese and Western Medicine Hospital, No. 18 Wanxiang North Road, Shiyang Street, Wuhou District, Chengdu 610000, Sichuan Province, China. shao_hui1986@163.com
Received: August 26, 2025
Revised: September 28, 2025
Accepted: November 17, 2025
Published online: January 27, 2026
Processing time: 148 Days and 1.7 Hours
Core Tip

Core Tip: This retrospective study compared epidural anesthesia (EA) with intravenous patient-controlled analgesia in patients undergoing pancreaticoduodenectomy. Using propensity score matching, the study found that EA significantly improved postoperative outcomes, including pain control, bowel function recovery, pulmonary complications, and patient satisfaction. EA was also associated with reduced inflammatory response and enhanced respiratory function. Subgroup analysis revealed greater benefits of EA in elderly patients and those with comorbidities. These findings support the use of EA as a key component of enhanced recovery protocols for major abdominal surgery.