Risk factors for enteral nutrition intolerance and its impact on prognosis in patients with severe acute pancreatitis
Chang-Mei Wu, Wen-Jun Zhu, Xi Chen, Min Liu, Yuan Feng, Mei Wang, Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Co-first authors: Chang-Mei Wu and Wen-Jun Zhu.
Author contributions: Wu CM and Zhu WJ did conceptualization, data curation, investigation, and writing the original draft, they contributed equally to this article, they are the co-first authors of this manuscript; Wu CM, Zhu WJ, and Chen X did formal analysis; Chen X, Liu M, and Feng Y did data collection; Liu M did investigation and software; Chen X and Feng Y did visualization; Wu CM, Zhu WJ, Feng Y, and Wang M did methodology; Wang M did conceptualization, project administration, supervision, writing review and editing, and funding acquisition; and all the authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of The First Affiliated Hospital of Anhui Medical University, approval No. PJ2024-05-90.
Informed consent statement: All patient information was anonymized and de-identified prior to analysis. The requirement for signed informed consent was waived by the institutional review board due to the retrospective nature of the study and minimal risk to participants.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: De-identified data and analysis code used in this study are available from the corresponding author upon reasonable request and with appropriate institutional approvals.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Mei Wang, MD, Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230022, Anhui Province, China.
mei_wang7065@sina.com
Received: August 15, 2025
Revised: September 24, 2025
Accepted: December 1, 2025
Published online: January 27, 2026
Processing time: 159 Days and 1.9 Hours
