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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2025; 17(9): 109159
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.109159
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.109159
Meta-analysis of predictive factors for delayed hemorrhage after endoscopic submucosal dissection in early-stage gastric carcinoma
Shou-Yuan Xu, Qi-Feng Lou, Ai-Yu Yu, Qi Ding, Endoscopy Center, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou 310003, Zhejiang Province, China
Yu-Feng Tong, Endoscopy Center, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou 310058, Zhejiang Province, China
Author contributions: Xu SY initiated the project, and designed the experiment and conducted clinical data collection; Lou QF, Yu AY and Tong YF performed postoperative follow-up and recorded data; Xu SY and Ding Q conducted a number of collation and statistical analysis, and wrote the original manuscript. All authors have read and approved the final manuscript.
Supported by Zhejiang Province Medical and Health Science and Technology Plan Project, No. 2024KY190.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qi Ding, Endoscopy Center, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Hangzhou 310003, Zhejiang Province, China. 18258283459@163.com
Received: May 20, 2025
Revised: June 18, 2025
Accepted: August 4, 2025
Published online: September 27, 2025
Processing time: 127 Days and 0.4 Hours
Revised: June 18, 2025
Accepted: August 4, 2025
Published online: September 27, 2025
Processing time: 127 Days and 0.4 Hours
Core Tip
Core Tip: Endoscopic submucosal dissection is a minimally invasive technique for early gastric cancer, enabling en bloc tumor removal and accurate pathological staging. This meta-analysis identifies long operation time, upper stomach lesions, and advanced age as key predictors of delayed bleeding, providing evidence-based insights for clinical risk stratification.