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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2025; 17(9): 109152
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.109152
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.109152
Therapeutic outcomes and predictors of efficacy for endoscopic variceal ligation plus propranolol in liver cirrhosis-related upper gastrointestinal bleeding
Dan-Feng Gong, Long Cheng, Department of Gastroenterology, Changde First People's Hospital, Changde 415000, Hunan Province, China
Author contributions: Gong DF and Cheng L contributed to conception, design, data analysis, and manuscript drafting and editing; Gong DF and Cheng L contributed to collection, assembly of data and revised the manuscript; Gong DF and Cheng L contributed to conception, resources, and manuscript review and editing; all authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Changde First People's Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Long Cheng, Chief Physician, Department of Gastroenterology, Changde First People's Hospital, No. 818 Renmin Road, Changde 415000, Hunan Province, China. cdchenglong2024@163.com
Received: June 24, 2025
Revised: July 25, 2025
Accepted: August 4, 2025
Published online: September 27, 2025
Processing time: 92 Days and 1.6 Hours
Revised: July 25, 2025
Accepted: August 4, 2025
Published online: September 27, 2025
Processing time: 92 Days and 1.6 Hours
Core Tip
Core Tip: To date, few studies have analyzed the therapeutic effects and influencing factors of endoscopic variceal ligation (EVL) plus propranolol for cirrhotic upper gastrointestinal bleeding (UGIB). This study enrolled 99 patients with cirrhosis complicated with UGIB, comparing the intervention effects between EVL plus propranolol and EVL alone. Consequently, the combined therapy achieved markedly better efficacy, with outstanding hemostasis, ameliorated hemodynamic conditions, facilitated postoperative recovery, and featured a notably lower rebleeding rate.