Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2025; 17(9): 107326
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.107326
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.107326
Risk modeling of delayed postoperative bleeding after endoscopic submucosal dissection for early colorectal cancer and precancerous lesions
Jun Qian, Shu-Sen Zheng, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Jun Qian, Department of Colorectal Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, Zhejiang Province, China
Ya-Li Tao, Endoscopy Center, Zhejiang Cancer Hospital, Hangzhou 310000, Zhejiang Province, China
Shu-Sen Zheng, National Health Commission Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, Zhejiang Province, China
Author contributions: Qian J designed the research and wrote the first manuscript; Qian J, Tao YL and Zheng SS conceived the research and analyzed the data; Qian J conducted the analysis and provided guidance for the research; and all authors reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Zhejiang Cancer Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shu-Sen Zheng, MD, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. shusenzheng@zju.edu.cn
Received: May 14, 2025
Revised: June 9, 2025
Accepted: July 25, 2025
Published online: September 27, 2025
Processing time: 133 Days and 1 Hours
Revised: June 9, 2025
Accepted: July 25, 2025
Published online: September 27, 2025
Processing time: 133 Days and 1 Hours
Core Tip
Core Tip: Currently, research on risk factors for delayed postoperative bleeding (DPOB) in patients undergoing endoscopic submucosal dissection for early colorectal cancer or precancerous lesions remains limited. This investigation set out to evaluate post-endoscopic submucosal dissection DPOB risk in these patients and to support more informed clinical management by identifying key influencing factors. Multiple lesions, lesions ≥ 3 cm in diameter, rectal lesion location, and marked fibrosis emerged as key independent predictors of DPOB. For patients exhibiting these risk factors, enhanced postoperative surveillance and tailored management strategies are therefore advised to improve their outcomes.